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anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) Antibodies

The protein encoded by ORAI1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Additionally we are shipping ORAI1 Kits (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ORAI1 84876 Q96D31
ORAI1 109305 Q8BWG9
ORAI1 304496 Q5M848
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Top anti-ORAI1 Antibodies at antibodies-online.com

Showing 10 out of 118 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ORAI1 Antibody Titration: 0.2-1 ug/mlPositive Contro... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ORAI1 Antibody Titration: 0.2-1 ug/mlPositive Contro... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ORAI1 Antibody (C-term) (ABIN658509) western blot analysis in A375 cel... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human prostate carcinoma reacted ... Western blot analysis of ORAI1 Antibody (Center) in A375 cell line and... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334452 (0.03µg/ml) staining of Human Placenta lysate (35µg protein... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of ORAI1 in human spleen tissue with this product... Western blot analysis of ORAI1 in human ovary tissue lysate with this ... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of ORAI1 in human spleen tissue with this product... Western blot analysis of ORAI1 in human ovary tissue lysate with this ... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human prostate carcinoma reacted ... Western blot analysis of ORAI1 Antibody (Center) (ABIN653318) in A375 ... 400 μL Log in to see 10 to 11 Days
$324.50
Details

ORAI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-ORAI1 Antibodies

  1. Human Polyclonal ORAI1 Primary Antibody for WB - ABIN658509 : Feng, Grice, Faddy, Nguyen, Leitch, Wang, Muend, Kenny, Sukumar, Roberts-Thomson, Monteith, Rao: Store-independent activation of Orai1 by SPCA2 in mammary tumors. in Cell 2010 (PubMed)
    Show all 4 references for ABIN658509

  2. Human Polyclonal ORAI1 Primary Antibody for EIA, IHC (p) - ABIN953931 : Calloway, Holowka, Baird: A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1. in Biochemistry 2010 (PubMed)
    Show all 3 references for ABIN953931

  3. Human Polyclonal ORAI1 Primary Antibody for IHC (p), WB - ABIN318921 : Lewis: Calcium signaling mechanisms in T lymphocytes. in Annual review of immunology 2001 (PubMed)
    Show all 2 references for ABIN318921

  4. Human Polyclonal ORAI1 Primary Antibody for WB - ABIN375074 : Vig, DeHaven, Bird, Billingsley, Wang, Rao, Hutchings, Jouvin, Putney, Kinet: Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. in Nature immunology 2007 (PubMed)

  5. Cow (Bovine) Polyclonal ORAI1 Primary Antibody for WB - ABIN2784058 : Peel, Liu, Hall: ORAI and store-operated calcium influx in human airway smooth muscle cells. in American journal of respiratory cell and molecular biology 2008 (PubMed)

More Antibodies against ORAI1 Interaction Partners

Zebrafish ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. The findings identify ORAI1 as an important regulator of cardiac and skeletal muscle function and provide evidence linking ORAI1-mediated calcium signaling to sarcomere integrity and cardiomyocyte function.

Xenopus laevis ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. The Orai1 actively recycles between an endosomal compartment and the cell membrane through a Rho-dependent endocytic pathway.

Silk Worm ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. STIM1 (show STIM1 Antibodies) and Orai1 are essential components of the signal transduction cascade that regulates sex pheromone production.

Human ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. Sigma1 receptors attenuates STIM1 (show STIM1 Antibodies) coupling to Orai1 and thereby inhibits SOCE.

  2. Orai1-dependent Ca(2 (show CA2 Antibodies)+) entry promotes atherogenesis possibly by promoting foam cell formation and vascular inflammation, rendering orai1 Ca(2 (show CA2 Antibodies)+) channel a potential therapeutic target against atherosclerosis.

  3. SARAF (show TMEM66 Antibodies) is constitutively expressed in the plasma membrane and interacts with Orai1.

  4. Overall high Orai3 (show ORAI3 Antibodies)/Orai1 ratios in human prostate epithelial cells and androgen-insensitive cancer cells contribute to their ROS (show ROS1 Antibodies) resistance and thereby may have a share in making the prostate one of the most prominent cancer susceptible organs

  5. Results identified common non-synonymous single nucleotide polymorphism located within exon 2 and a rare 6 base-pair in-frame insertion variant in ORAI1 gene associated with Kawasaki disease.

  6. Studies suggest that STIM1 (show STIM1 Antibodies) protein and calcium channel Orai1-mediated Ca2 (show CA2 Antibodies)+ signaling are the potential target for cancer therapy.

  7. Studies indicate that Ca(2 (show CA2 Antibodies)+) sensor STIM1 (show STIM1 Antibodies) and calcium channel Orai1 upregulation in cancer cells results in Ca2 (show CA2 Antibodies) + homeostasis remodeling and cell proliferation.

  8. we conclude that NO, cGMP, and PKG (show PRKG1 Antibodies) inhibit the hypertrophy of hESC-CMs (show Cd2ap Antibodies) via PKG (show PRKG1 Antibodies)-mediated phosphorylation on Orai1-Ser (show SIGLEC1 Antibodies)-34.

  9. Studied the possible protective models of breast cancer association in terms of the SNPs of ORAI1 gene using a particle swarm optimization (PSO (show PIPOX Antibodies)) algorithm.

  10. These first recordings of single-channel Orai1 currents reveal unexpected dynamics, and when paired with CRAC-activating domain association, support multiple single-channel states.

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. Orai1 (show TMEM132A Antibodies)-dependent Ca(2 (show CA2 Antibodies)+) entry promotes atherogenesis possibly by promoting foam cell formation and vascular inflammation, rendering orai1 (show TMEM132A Antibodies) Ca(2 (show CA2 Antibodies)+) channel a potential therapeutic target against atherosclerosis.

  2. alternative translation initiation of the Orai1 (show TMEM132A Antibodies) message produces at least three types of Ca(2 (show CA2 Antibodies)+) channels with distinct signaling and regulatory properties.

  3. Orai1 (show TMEM132A Antibodies) and STIM1 (show STIM1 Antibodies) have roles in inhibiting matrix protein expression

  4. SOCE blockers or ablation of STIM1 (show STIM1 Antibodies), STIM2 (show Stim2 Antibodies), or Orai1 (show TMEM132A Antibodies) severely impaired nucleotide-induced migration and phagocytosis in microglia.

  5. Our data establish Orai1 (show TMEM132A Antibodies) as key signal mediator of C5aR (show C5AR1 Antibodies) activation, contributing to inflammation

  6. Orai1 (show TMEM132A Antibodies) store-operated calcium channels have an essential role in lactation

  7. TRPC6 (show TRPC6 Antibodies) activity can occur independently of the physical interaction with Orai1 (show TMEM132A Antibodies)

  8. Data show that increased activity of STIM1 (show STIM1 Antibodies)-Orai1 (show TMEM132A Antibodies) complex inducing enhanced Ca(2 (show CA2 Antibodies)+) influx is a disease determinant in muscular dystrophy.

  9. STIM1 (show STIM1 Antibodies), STIM2 (show Stim2 Antibodies), and CRAC channel function play distinct but synergistic roles in CD4 (show CD4 Antibodies)+ and CD8 (show CD8A Antibodies)+ T cells during antiviral immunity

  10. The calcium release-activated calcium channel Orai1 (show TMEM132A Antibodies) represents a crucial component in hypertrophic compensation and the development of dilated cardiomyopathy

ORAI1 Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).

Gene names and symbols associated with ORAI1

  • ORAI calcium release-activated calcium modulator 1b (orai1b) antibody
  • ORAI calcium release-activated calcium modulator 1 (orai1) antibody
  • ORAI calcium release-activated calcium modulator 1 (ORAI1) antibody
  • ORAI calcium release-activated calcium modulator 1 (Orai1) antibody
  • ORAI calcium release-activated calcium modulator 1 (LOC100218031) antibody
  • ORAI calcium release-activated calcium modulator 2 (orai2) antibody
  • CRACM1 antibody
  • D730049H07Rik antibody
  • im:7146264 antibody
  • LOC100218031 antibody
  • orai-1 antibody
  • ORAI1 antibody
  • orai2 antibody
  • ORAT1 antibody
  • RGD1311873 antibody
  • Tmem142a antibody
  • tmem142b antibody
  • zgc:109721 antibody

Protein level used designations for ORAI1

ORAI calcium release-activated calcium modulator 1 , calcium release-activated calcium channel protein 1 , protein orai-1 , transmembrane protein 142A , protein orai-2 , transmembrane protein 142B , calcium release-activated calcium modulator 1 , calcium release-activated calcium channel 1

GENE ID SPECIES
402892 Danio rerio
403390 Xenopus laevis
473293 Pan troglodytes
700190 Macaca mulatta
100125061 Xenopus (Silurana) tropicalis
100188931 Bombyx mori
100218031 Taeniopygia guttata
84876 Homo sapiens
486261 Canis lupus familiaris
100154923 Sus scrofa
517688 Bos taurus
109305 Mus musculus
304496 Rattus norvegicus
416845 Gallus gallus
734537 Xenopus laevis
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