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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) Antibodies

PRDM1 encodes a protein that acts as a repressor of beta-interferon gene expression. Additionally we are shipping PR Domain Containing 1, with ZNF Domain Proteins (9) and PR Domain Containing 1, with ZNF Domain Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRDM1 639 O75626
PRDM1 12142 Q60636
PRDM1 309871  
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Top anti-PR Domain Containing 1, with ZNF Domain Antibodies at antibodies-online.com

Showing 10 out of 180 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 25 μL Log in to see 6 to 8 Days
$253.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PRDM1 Antibody Titration: 2.5ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-PRDM1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: SH-SYSY cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunofluorescence of Blimp-1 in mouse lung tissue with AP30154PU-N Blimp-1 antibody at 20 μg/ml. Western blot analysis of Blimp-1 in A549 cell lysate with AP30154PU-N Blimp-1 antibody at (A) 0.5 and (B) 1μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of Blimp-1 in mouse lung tissue with Blimp-1 antibody at 5 μg/ml. Western blot analysis of Blimp-1 in mouse lung tissue lysate with AP30155PU-N Blimp-1 antibody at (A) 0.5 and (B) 1μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blots using affinity purified anti-PRDM1/BLIMP1 antibody show detection of overexpressed PRDM1/BLIMP1 in whole transfected Raji cell lysate (lane 2) at ~88kDa. Lane 1 shows mock transfection in whole Raji cell lysate. Detection of endogenous PRDM1/BLIMP1 (lane 4) is illustrated in human plasma cell nuclear extract, but not in Raji whole cell nuclear extract (lane 3). The identity of the lower dark band at ~50-60kDa is unknown. Primary antibody was used at a 1:1000 dilution in 5% PBS-Tween. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Rabbit Un-conjugated WB PRDM1 Antibody (N-term) (ABIN658442) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the PRDM1 antibody detected the PRDM1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

PRDM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PR Domain Containing 1, with ZNF Domain Antibodies

  1. Human Polyclonal PRDM1 Primary Antibody for EIA, IHC (p) - ABIN499477 : Angelin-Duclos, Cattoretti, Lin, Calame: Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 3 references for ABIN499477

  2. Human Monoclonal PRDM1 Primary Antibody for ELISA, WB - ABIN1724737 : Ancelin, Lange, Hajkova, Schneider, Bannister, Kouzarides, Surani: Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. in Nature cell biology 2006 (PubMed)
    Show all 3 references for ABIN1724737

  3. Human Polyclonal PRDM1 Primary Antibody for EIA, WB - ABIN401478 : Morris, Beresford, Mooney, Boss: Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation. in Molecular and cellular biology 2002 (PubMed)
    Show all 3 references for ABIN401478

  4. Human Polyclonal PRDM1 Primary Antibody for EIA, IF - ABIN499475 : Reimold, Iwakoshi, Manis, Vallabhajosyula, Szomolanyi-Tsuda, Gravallese, Friend, Grusby, Alt, Glimcher: Plasma cell differentiation requires the transcription factor XBP-1. in Nature 2001 (PubMed)
    Show all 3 references for ABIN499475

  5. Cow (Bovine) Polyclonal PRDM1 Primary Antibody for EIA, WB - ABIN487993 : Chang, Angelin-Duclos, Calame: BLIMP-1: trigger for differentiation of myeloid lineage. in Nature immunology 2001 (PubMed)

  6. Chicken Polyclonal PRDM1 Primary Antibody for WB - ABIN2780353 : González-García, Ocaña, Jiménez-Gómez, Campos-Caro, Brieva: Immunization-induced perturbation of human blood plasma cell pool: progressive maturation, IL-6 responsiveness, and high PRDI-BF1/BLIMP1 expression are critical distinctions between antigen-specific and nonspecific plasma cells. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  7. Cow (Bovine) Polyclonal PRDM1 Primary Antibody for IHC, WB - ABIN2792524 : Diehl, Schmidlin, Nagasawa, van Haren, Kwakkenbos, Yasuda, Beaumont, Scheeren, Spits: STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against PR Domain Containing 1, with ZNF Domain Interaction Partners

Rabbit PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. BLIMP1 (PRDM1)expression begins throughout the hypoblast at stage 1 and emerges in single primordial germ cell (PGC (show PGC Antibodies)) precursors in the posterior epiblast at stage 2.

Fruit Fly (Drosophila melanogaster) PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. Blimp-1 gene is transcribed during prepupal development when the ecdysteroid titer is high, but the expressed mRNA degrades rapidly.

  2. Blimp-1 regulates terminal differentiation of the tracheal system in the Drosophila embryo.

  3. These results suggest that the transient transcriptional repressor dBlimp-1 is important for determining developmental timing in the ecdysone-induced pathway.

Zebrafish PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. Expression of the M- and N-cadherins, previously implicated in driving adaxial cell migration, is largely unaffected by loss of Prdm1a function, suggesting that differential cadherin expression is not sufficient for adaxial cell migration

  2. Prdm1a functions as both a transcriptional activator and repressor during neural crest development.

  3. identify sox6 cis (show CISH Antibodies)-regulatory sequences that drive fast-twitch-specific expression in a Prdm1a-dependent manner

  4. prdm1a expression is upregulated in the absence of Notch (show NOTCH1 Antibodies) function, and inhibiting Notch (show NOTCH1 Antibodies) signaling fails to rescue prdm1a mutants

  5. prdm1a Regulates sox10 (show SOX10 Antibodies) and islet1 (show ISL1 Antibodies) in the development of neural crest and Rohon-Beard sensory neurons.

  6. These results indicate an essential role for prdm1a in the development of the zebrafish craniofacial skeleton.

  7. Here we show that the gene u-boot (ubo), a mutation in which disrupts the induction of embryonic slow-twitch fibers, encodes the zebrafish homolog of Blimp-1

  8. The transcriptional regulator Blimp-1 plays a role in the inception of Neural Crest progenitor fate through BMP signalling.

  9. prdm1/blimp1 has roles in embryo patterning and organogenesis

  10. prdm1 functions to promote the cell fate specification of both neural crest cells and sensory neurons

Human PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. Blimp-1 regulates the transcription of CS1 (show CSH1 Antibodies) gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.

  2. Antineoplastic effects of liposomal short interfering RNA treatment targeting BLIMP1/PRDM1 in primary effusion lymphoma.

  3. The interaction between EBV-miR (show MLXIP Antibodies)-BHRF1-2 and PRDM1 may be one of the mechanisms by which EBV-miRBHRF1-2 promotes Epstein-Barr virus lymphomagenesis.

  4. heterozygous deletion of 6q21 and/or PRDM1 was frequently detected in extranodal NK/T cell lymphoma, nasal type and correlated with downregulation of PRDM1.

  5. KLF4 (show KLF4 Antibodies), together with BLIMP1, plays a critical role in mediating lytic Epstein-Barr virus reactivation in epithelial cells.

  6. Our findings suggest a previously unrecognized role of PRDM1 and human parvovirus B19 in the pathogenesis of Hashimoto thyroiditis

  7. Blimp1-deficient effector T cells fail to produce IL-10 (show IL10 Antibodies), and deficiency in Tr-1 (show TNFRSF11B Antibodies) cell function leads to uncontrolled Th17 cell-driven CNS pathology without the need to stabilize the Th17 phenotype with IL-23 (show IL23A Antibodies)

  8. Positional mapping of PRKD1 (show PRKD1 Antibodies), NRP1 (show NELL1 Antibodies) and PRDM1 as novel candidate disease genes in truncus arteriosus

  9. Blimp-1 expression in dendritic cells can alter an innate inflammatory response by modulating the activation of myeloid cells

  10. Data show that vascular (show FOXG1 Antibodies) endothelial growth factor (VEGF) upregulates the transcription repressor PRD1-BF1 protein in endothelial cells.

Mouse (Murine) PR Domain Containing 1, with ZNF Domain (PRDM1) interaction partners

  1. The escape of a fraction of Primordial germ cells from the Prdm1 deletion was sufficient to recover fairly normal germ cell pools, both in male and female adults

  2. There is a common program of effector T cell differentiation that is regulated by IL-2 and IL-12 signaling and the combined activities of the transcriptional regulators Blimp-1 and T-bet.

  3. Reduction of HDAC3 (show HDAC3 Antibodies) or NCoR1 (show NCOR1 Antibodies) expression by RNA interference in B cells resulted in an increased Prdm1 mRNA expression.

  4. TCF1 (show HNF1A Antibodies) is required for the T follicular helper cell response to viral infection functioning through negative feedback loops with IL-2 (show IL2 Antibodies) and Blimp1.

  5. Blimp1 was dispensable for survival of plasma cells. Blimp-1-deficient plasma cells retained their transcriptional identity but lost the ability to secrete antibody. Blimp-1 regulated many components of the unfolded protein response.

  6. Blimp1 promoted the migration and adhesion of plasmablasts, silenced B cell-specific gene expression, antigen presentation and class-switch recombination in plasmablasts, and induced immunoglobulin gene transcription and secretion.

  7. In a genetically engineered mouse model of soft tissue sarcoma that loss of GCN2 has no effect on tumor growth or animal survival.

  8. Blimp-1 likely has distinct gene-regulating activities depending on the inflammatory or anti-inflammatory enhancer landscape created by a multi-factorial transcriptional complex

  9. From these results, we defined the distinct functions of Blimp-1 and Akt (show AKT1 Antibodies) and provided mechanistic insights into the acquisition of pluripotency in Primordial germ cells.

  10. LPS (show TLR4 Antibodies)-PG completely abrogates RANKL (show TNFSF11 Antibodies)-induced gene expression of B lymphocyte-induced maturation protein-1 (Blimp1), a global transcriptional repressor of anti-osteoclastogenic genes encoding Bcl6 (show BCL6 Antibodies), IRF8 (show IRF8 Antibodies), and MafB (show MAFB Antibodies)

PR Domain Containing 1, with ZNF Domain (PRDM1) Antigen Profile

Protein Summary

This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Gene names and symbols associated with PRDM1

  • PR domain containing 1, with ZNF domain (PRDM1) antibody
  • PR domain containing 1, with ZNF domain (LOC100338324) antibody
  • Blimp-1 protein (Blimp-1) antibody
  • CG5249 gene product from transcript CG5249-RB (Blimp-1) antibody
  • blimp-1 (CpipJ_CPIJ007425) antibody
  • PR domain containing 1a, with ZNF domain (prdm1a) antibody
  • PR domain containing 1, with ZNF domain (prdm1) antibody
  • B lymphocyte induced maturation protein 1 (prdm1) antibody
  • PR domain containing 1, with ZNF domain (Prdm1) antibody
  • Blimp-1 antibody
  • BLIMP1 antibody
  • CG5249 antibody
  • dBlimp-1 antibody
  • dBlimp1 antibody
  • Dmel\\CG5249 antibody
  • GB11750 antibody
  • MGC52536 antibody
  • nrd antibody
  • PRDI-BF1 antibody
  • PRDM1 antibody
  • ubo antibody
  • wu:fb99c12 antibody
  • xblimp1 antibody
  • zgc:91885 antibody
  • ZNFPR1A1 antibody

Protein level used designations for PRDM1

PR domain containing 1, with ZNF domain , Blimp-1 protein , Blimp-1-PA , Blimp-1-PB , Blimp-1-PC , Blimp-1-PD , Blimp-1-PE , CG5249-PA , CG5249-PB , CG5249-PC , CG5249-PD , CG5249-PE , dBlimp1 , blimp-1 , B lymphocyte-induced maturation protein 1 , PR domain zinc finger protein 1 , PR domain-containing 1 , U boot , narrowminded , u-boot , B lymphocyte induced maturation protein 1 , PR domain zinc finger protein 1-like , B-lymphocyte-induced maturation protein 1 , BLIMP-1 , PRDI-binding factor-1 , beta-interferon gene positive-regulatory domain I binding factor , B lymphocyte induced maturation protein , PR domain containing 1 with ZNF domain , PR domain-containing protein 1 , beta-interferon gene positive regulatory domain I-binding factor

GENE ID SPECIES
100154284 Sus scrofa
100338324 Oryctolagus cuniculus
408295 Apis mellifera
38638 Drosophila melanogaster
6039439 Culex quinquefasciatus
323473 Danio rerio
380265 Xenopus laevis
446070 Takifugu rubripes
462904 Pan troglodytes
493207 Xenopus (Silurana) tropicalis
696757 Macaca mulatta
100071967 Equus caballus
100401970 Callithrix jacchus
100442042 Pongo abelii
100474321 Ailuropoda melanoleuca
100548130 Meleagris gallopavo
100560171 Anolis carolinensis
100585120 Nomascus leucogenys
100619194 Monodelphis domestica
639 Homo sapiens
12142 Mus musculus
445340 Gallus gallus
481947 Canis lupus familiaris
538384 Bos taurus
309871 Rattus norvegicus
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