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anti-Potassium Channel, Subfamily K, Member 5 (KCNK5) Antibodies

KCNK5 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNK5 8645 O95279
KCNK5 16529  
KCNK5 364241  
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Top anti-KCNK5 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KCNK5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-KCNK5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with KCNK5 antibody ABIN214786 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB KCNK5 antibody used at 0.5 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged KCNK5 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB   50 μL Log in to see 11 to 16 Days
$620.71
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 11 to 16 Days
$553.14
Details

KCNK5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
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,
Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-KCNK5 Antibodies

  1. Human Polyclonal KCNK5 Primary Antibody for IHC, WB - ABIN350413 : Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. in Molecular cell 2008 (PubMed)
    Show all 5 references for ABIN350413

  2. Cow (Bovine) Polyclonal KCNK5 Primary Antibody for WB - ABIN2780207 : Rusznák, Pocsai, Kovács, Pór, Pál, Bíró, Szücs: Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum. in Cellular and molecular life sciences : CMLS 2004 (PubMed)

More Antibodies against KCNK5 Interaction Partners

Human Potassium Channel, Subfamily K, Member 5 (KCNK5) interaction partners

  1. Potassium channel (show KCNAB2 Antibodies) TASK2 drives human NK-cell proliferation and cytolytic function.

  2. Mutant genes (CELA1 (show CELA1 Antibodies), HSPG2 (show HSPG2 Antibodies), and KCNK5) in Balkan endemic nephropathy patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, tightly connected to process of angiogenesis.

  3. The TASK-2 channel lower expression represents a hallmark of aldosterone-producing adenoma causing aldosteronism and is associated with a higher expression of hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-23 and hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-34.

  4. Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells

  5. Disease activity in rheumatoid arthritis patients correlates strongly with K(2P)5.1 expression levels in CD4 (show CD4 Antibodies)+ T lymphocytes in the peripheral blood

  6. 17beta-estradiol induces the expression of KCNK5 via ERalpha (show ESR1 Antibodies)(+) in breast cancer cells, and this channel plays a role in regulating proliferation in these cell lines.

  7. Data suggest that the cytokine receptor (show EBI3 Antibodies)-coupled JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) pathway is upstream of the swelling-induced phosphorylation and activation of TASK-2 in Ehrlich ascites tumor cells.

  8. We here identify and characterize K2P5.1 as a critical player of T-cell effector function; selective targeting of K(2P)5.1 may hold therapeutic promise for multiple sclerosis and putatively other T-cell-mediated disorders.

  9. TASK-2 does not possess a histidine residue at homologous position. Inclusion of such a residue failed to produce expected increase in pH sensitivity; instead, a slight decrease was observed

  10. TASK-2 is not highly expressed in cerebellum

Mouse (Murine) Potassium Channel, Subfamily K, Member 5 (KCNK5) interaction partners

  1. KCNK5 channels are indispensable for the maintenance of hearing. KCNK5 is mainly found in outer sulcus Claudius', Boettcher's and root cells.

  2. The data identify GPR4 (show GPR4 Antibodies) and TASK-2 as distinct, parallel, and essential central mediators of respiratory chemosensitivity.

  3. TASK-2 is upregulated under hypoxia in a HIF-1alpha (show HIF1A Antibodies)-dependent manner in B cells.

  4. The strong physiological impairment of KCNK5 in Ehrlich cells after long-term hypotonic stimulation is predominantly due to down-regulation of the KCNK5 protein synthesis.

  5. data are compatible with the concept that TASK-2 channels are modulated by Gbetagamma subunits of heterotrimeric G protein; propose that this modulation is a novel way in which TASK-2 can be tuned to its physiological functions

  6. alkaline-activated TASK-2 channels contribute to pH sensitivity in retrotrapezoid nucleus neurons

  7. Kv1.3 (show KCNA3 Antibodies)/TASK2 channels appear to be mainly responsible for regulatory volume decrease in murine T-lymphocytes.

  8. a cycle of protonation/deprotonation of pH(o)-sensing arginine 224 side chain gates the TASK-2 channel by electrostatically tuning the conformational stability of its selectivity filter.

  9. The authors report for the first time the expression of TASK-2 in B cells and surmise that the upregulation of TASK-2 by B cell receptor ligation is associated with the apoptosis of immature B cells.

  10. intracellular pH, together with pH(o), is a critical determinant of TASK-2 activity and therefore of its physiological function

KCNK5 Antigen Profile

Protein Summary

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.

Gene names and symbols associated with KCNK5

  • potassium channel, subfamily K, member 5b (kcnk5b) antibody
  • potassium channel, subfamily K, member 5 (KCNK5) antibody
  • potassium channel, subfamily K, member 5 (kcnk5) antibody
  • potassium channel, subfamily K, member 5 (Kcnk5) antibody
  • K2p5.1 antibody
  • kcnk5 antibody
  • TASK-2 antibody
  • TASK2 antibody
  • zgc:63921 antibody

Protein level used designations for KCNK5

potassium channel, subfamily K, member 5 , potassium channel subfamily K member 5-like , K2P5.1 potassium channel , TWIK-related acid-sensitive K(+) channel 2 , TWIK-related acid-sensitive K+ channel 2 , acid-sensitive potassium channel protein TASK-2 , potassium channel subfamily K member 5 , potassium channel, subfamily K, member 1 (TASK-2) , potassium inwardly-rectifying channel, subfamily K, member 5

GENE ID SPECIES
393606 Danio rerio
421424 Gallus gallus
496362 Xenopus laevis
100436248 Pongo abelii
8645 Homo sapiens
481780 Canis lupus familiaris
782166 Bos taurus
100009446 Oryctolagus cuniculus
16529 Mus musculus
364241 Rattus norvegicus
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