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anti-Ring Finger Protein 125 (RNF125) Antibodies

RNF125 encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. Additionally we are shipping RNF125 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF125 67664 Q9D9R0
RNF125 361296  
RNF125 54941 Q96EQ8
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Top anti-RNF125 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged RNF125 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RNF125 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: THP-1 cell lysate WB Suggested Anti-RNF125  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562/HT-29 cells, using RNF125 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of RNF125 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RNF125 expression in HEK293T (A), THP1 (B), 129Sv (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with RNF125 antibody ABIN351544 at 1:100 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Chimpanzee Rabbit Un-conjugated IHC (p), WB 50 μL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$683.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details

RNF125 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RNF125 Antibodies

  1. Human Monoclonal RNF125 Primary Antibody for ELISA, WB - ABIN393443 : Giannini, Gao, Bijlmakers: T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain. in The Biochemical journal 2008 (PubMed)
    Show all 5 references for ABIN393443

  2. Human Polyclonal RNF125 Primary Antibody for ELISA, WB - ABIN185241 : Chu, Pardo, Zhao, Li, Pali, Shen, Qu, Yu, Huang, Yu, Masuda, Molineaux, Kolbinger, Aversa, de Vries, Payan, Liao: Systematic identification of regulatory proteins critical for T-cell activation. in Journal of biology 2004 (PubMed)

More Antibodies against RNF125 Interaction Partners

Mouse (Murine) Ring Finger Protein 125 (RNF125) interaction partners

  1. Data indicate that brain from Japanese encephalitis virus (JEV)-infection showed a (show UTS2R Antibodies)reciprocal correlation between microRNA miR-15b levels and the ex (show MLXIP Antibodies)pression of ring finger protein 125 (RNF125).

  2. RNF125 is enhanced by IFN, these functions constitute a negative regulatory loop circuit for IFN production

Human Ring Finger Protein 125 (RNF125) interaction partners

  1. we identified the downregulation of the ubiquitin ligase RNF125 in BRAFi-resistant melanomas

  2. Results indicate that the nucleotide sequence in the 3' untranslated region (3' UTR (show UTS2R Antibodies)) of ring finger protein 125 (RNF125) is a potential microRNA miR (show MLXIP Antibodies)-15b targeting site.

  3. studies of the RNF125 pathway point to upregulation of RIG-I (show DDX58 Antibodies)-IPS1 (show MAVS Antibodies)-MDA5 (show IFIH1 Antibodies) and/or disruption of the PI3K (show PIK3CA Antibodies)-AKT (show AKT1 Antibodies) and interferon (show IFNA Antibodies) signaling pathways as the putative final effectors

  4. In controls, RNF125 is the highest expressed gene, whereas in HIV infection progressors, RIG-I (show DDX58 Antibodies) is either the highest expressed gene or is expressed similarly to RNF125 and TRIM25 (show TRIM25 Antibodies).

  5. study reports human bocavirus VP2 modulates IFN pathway by targeting the ring finger protein 125, a negative regulator of type I IFN signaling, which conjugates Lys (show LYZ Antibodies)(48)-linked ubiquitination to retinoic acid-inducible gene-I (show DDX58 Antibodies) and leads to the proteasome-dependent degradation of RIG-I (show DDX58 Antibodies)

  6. These results suggest that RNF125/TRAC-1 could function to recruit host factor(s) controlling HIV-1 transcription to the ubiquitin-proteasome pathway.

  7. TRAC-1 (show NCOR1 Antibodies) associates with membranes and is excluded from the nucleus through myristoylation

RNF125 Antigen Profile

Protein Summary

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.

Gene names and symbols associated with RNF125

  • ring finger protein 125 (RNF125) antibody
  • ring finger protein 125 (Rnf125) antibody
  • ring finger protein 125, E3 ubiquitin protein ligase (RNF125) antibody
  • 4930553F04Rik antibody
  • TRAC-1 antibody
  • TRAC1 antibody

Protein level used designations for RNF125

E3 ubiquitin-protein ligase RNF125 , T-cell RING activation protein 1 , T-cell ring protein identified in activation screen

GENE ID SPECIES
519541 Bos taurus
67664 Mus musculus
361296 Rattus norvegicus
54941 Homo sapiens
743809 Pan troglodytes
490498 Canis lupus familiaris
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