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anti-Ring Finger Protein 128 (RNF128) Antibodies

The protein encoded by RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. Additionally we are shipping Ring Finger Protein 128 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF128 66889 Q9D304
RNF128 79589 Q8TEB7
RNF128 315911  
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Top anti-Ring Finger Protein 128 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RNF128 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate WB Suggested Anti-RNF128  Antibody Titration: 1.25 µg/mL  Positive Control: HepG2 cell lysate  RNF128 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RNF128 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate WB Suggested Anti-RNF128  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: COLO205 cell lysate  RNF128 is supported by BioGPS gene expression data to be expressed in COLO205 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB TBC1D3F Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TBC1D3F antibody detected the TBC1D3F protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Mouse Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Mouse Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

RNF128 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human , ,


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Rat (Rattus) ,


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Top referenced anti-Ring Finger Protein 128 Antibodies

  1. Cow (Bovine) Polyclonal RNF128 Primary Antibody for WB - ABIN2774780 : Soares, Seroogy, Skrenta, Anandasabapathy, Lovelace, Chung, Engleman, Fathman: Two isoforms of otubain 1 regulate T cell anergy via GRAIL. in Nature immunology 2003 (PubMed)

More Antibodies against Ring Finger Protein 128 Interaction Partners

Mouse (Murine) Ring Finger Protein 128 (RNF128) interaction partners

  1. Grail plays a critical role in controlling Th2 cell development through a negative feedback loop by targeting STAT6 (show STAT6 Antibodies) for degradation.

  2. GRAIL-expressing T cells expressed regulatory T cell markers and showed suppressive effects in murine dextran sodium salt-induced colitis.

  3. findings reveal a novel association of the increased GRAIL expression with impaired CD4 (show CD4 Antibodies) T cell proliferation

  4. Data reveal that GRAIL regulates proteins involved in the actin cytoskeletal organization, thereby maintaining the unresponsive state of anergic T cells.

  5. GRAIL, by mediating TCR-CD3 (show CD3E Antibodies) degradation, regulates naive T cell tolerance induction and Treg cell function

  6. a biochemical pathway composed of GRAIL and/or GRAIL-interacting proteins is important in the development of the CD4 (show CD4 Antibodies) T cell anergic phenotype in vivo.

  7. Down-regulation of CD40L (show CD40LG Antibodies) occurred following ectopic expression of GRAIL in naive T cells from CD40 (show CD40 Antibodies)(-/-) mice

  8. GRAIL in the liver is essential for maintenance of normal glucose and lipid metabolism in living animals.

  9. the decline in Th2 cell responsiveness during chronic schistosomiasis is the net result of the upregulation of GRAIL expression in response to repeated antigen stimulation

  10. endogenous GRAIL regulates general cell cycle and proliferation of primary naive CD4 (show CD4 Antibodies) T cells.

Human Ring Finger Protein 128 (RNF128) interaction partners

  1. results show that expression of GRAIL is uniquely regulated by the specific miRNA in intestinal mucosa, and suggest that GRAIL may associate with the pathophysiology of Crohn's disease

  2. study shows that Grail has a novel, p53 (show TP53 Antibodies)-dependent role in regulating the cell cycle and apoptosis

  3. Forced expression of GRAIL in a T cell line from a T-cell receptor transgenic mouse is sufficient for conversion of these cells to a regulatory phenotype.

  4. Inhibition of T cell activation is not due to apoptosis or disruption of proximal T- cell receptor signaling, but is associated with up-regulation of GRAIL in CD4+ T cells, with modest effects on other E3 ubiquitin ligases.

  5. GRAIL expression was significantly higher in patients with ulcerative colitis in remission than in patients with active disease and in healthy volunteers.

  6. GRAIL captures and then ubiquitinates transmembrane proteins across the cell membrane

  7. endogenous GRAIL regulates general cell cycle and proliferation of primary naive CD4 (show CD4 Antibodies) T cells.

  8. GRAIL can down-modulate the expression of CD83 antigen (show CD83 Antibodies) on CD4 (show CD4 Antibodies) T cells.

Ring Finger Protein 128 (RNF128) Antigen Profile

Protein Summary

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with RNF128

  • ring finger protein 128a (rnf128a) antibody
  • ring finger protein 128 (RNF128) antibody
  • ring finger protein 128 (Rnf128) antibody
  • ring finger protein 128, E3 ubiquitin protein ligase (RNF128) antibody
  • ring finger protein 128, E3 ubiquitin protein ligase (Rnf128) antibody
  • ring finger protein 128, E3 ubiquitin protein ligase (rnf128) antibody
  • 1300002C13Rik antibody
  • AI987883 antibody
  • grail antibody
  • greul1 antibody
  • RGD1566282 antibody
  • rnf128 antibody
  • wu:fb57h05 antibody
  • zgc:77843 antibody

Protein level used designations for RNF128

E3 ubiquitin-protein ligase RNF128 , ring finger protein 128 , gene related to anergy in lymphocytes protein , goliath-related E3 ubiquitin-protein ligase 1 , goliath-related E3 ubiquitin ligase 1

GENE ID SPECIES
322325 Danio rerio
422382 Gallus gallus
66889 Mus musculus
79589 Homo sapiens
492051 Canis lupus familiaris
535869 Bos taurus
315911 Rattus norvegicus
779098 Xenopus laevis
100171545 Pongo abelii
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