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SH3GLB1 encodes a SRC homology 3 domain-containing protein. Additionally we are shipping SH3GLB1 Proteins (9) and many more products for this protein.
Showing 10 out of 128 products:
Human Monoclonal SH3GLB1 Primary Antibody for ICC, IF - ABIN4308128
Karbowski, Jeong, Youle: Endophilin B1 is required for the maintenance of mitochondrial morphology. in The Journal of cell biology 2004
Show all 18 references for ABIN4308128
Human Polyclonal SH3GLB1 Primary Antibody for EIA, IF - ABIN499465
Lockshin, Osborne, Zakeri: Cell death in the third millennium. in Cell death and differentiation 2000
Show all 4 references for ABIN499465
Human Polyclonal SH3GLB1 Primary Antibody for EIA, IHC (p) - ABIN360475
Lee, Jeong, Soung, Nam, Lee, Yoo, Lee: Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. in Pathology 2006
Show all 3 references for ABIN360475
Human Polyclonal SH3GLB1 Primary Antibody for ICC, IF - ABIN441165
Mir, George, Zahoor, Harms, Guinn, Sarvetnick: Inhibition of Autophagic Turnover in ?-Cells by Fatty Acids and Glucose Leads to Apoptotic Cell Death. in The Journal of biological chemistry 2015
Cow (Bovine) Polyclonal SH3GLB1 Primary Antibody for WB - ABIN374106
Takahashi, Karbowski, Yamaguchi, Kazi, Wu, Sebti, Youle, Wang: Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. in Molecular and cellular biology 2005
These findings thus identify Bif-1 as a novel regulator of lipid homeostasis to prevent the pathogenesis of obesity and its associated metabolic complications.
these data reveal an Irgm1 (show IRGM Antibodies)-dependent mechanism that promotes the tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy
Our findings suggest that endophilin-B1 is a key mediator of a feed-forward mechanism of Alzheimer's disease pathogenesis
selective autophagy regulates the basal and atrophy-induced turnover of the pentameric transmembrane protein, CHRN, and that TRIM63 (show TRIM63 Antibodies), together with SH3GLB1 and SQSTM1 (show SQSTM1 Antibodies) regulate this process.
these data suggest that Bif-1 is essential for the maintenance of mitochondrial morphology and function in neurons
Bif-1 haploinsufficiency attenuates mitophagy and results in the promotion of chromosomal instability, which enables tumor cells to efficiently bypass the oncogenic/metabolic pressures for apoptosis.
findings not only establish Cdk5 (show CDK5 Antibodies) as a critical regulator of autophagy induction, but also reveal a role for Cdk5 (show CDK5 Antibodies) and EndoB1 in the pathophysiology of Parkinson's disease through modulating autophagy
These findings suggest that Bif-1 acts as a critical regulator of Atg9 (show ATG9A Antibodies) puncta formation presumably by mediating Golgi fission for autophagosome biogenesis during starvation.
Bif-1 is an important component of the mitochondrial pathway for apoptosis as a novel Bax (show BAX Antibodies)/Bak (show BAK1 Antibodies) activator, and loss of this proapoptotic molecule may contribute to tumorigenesis.
A potential role for endophilin B1t (show TUBB Antibodies) in mammalian spermatogenesis is discussed within the context of the PP1c gamma knockout testis phenotype.
Bif-1 (show ZBTB24 Antibodies) is involved in prostate cancer tumorigenesis and acts as a suppressor in prostate cancer progression.
endophilin B1 mediated the biological function of EGFR (show EGFR Antibodies) in cancer cell proliferation through regulating the EGFR (show EGFR Antibodies) endocytic trafficking and downstream signaling.
these data reveal an Irgm1 (show IRGM Antibodies)-dependent mechanism that promotes the tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1 (show ZBTB24 Antibodies)-dependent autophagy
Data suggest that activated autophagy is associated with the progression of pancreatic ductal adenocarcinoma and that the overexpression of autophagy-related proteins Atg5 (show ATG5 Antibodies), Ambra1 (show AMBRA1 Antibodies), beclin-1 (show BECN1 Antibodies), LC3B (show MAP1LC3B Antibodies) and Bif-1 (show ZBTB24 Antibodies) is significantly correlated with poor outcome.
these data suggest a novel function for Bif-1 (show ZBTB24 Antibodies) as a suppressor of breast cancer cell migration by promoting EGFR (show EGFR Antibodies) degradation through the regulation of endosome maturation
The expression of Bif-1 (show ZBTB24 Antibodies) is downregulated in a subset of pancreatic ductal adenocarcinoma. This novel finding is in agreement with the tumor suppressor function of Bif-1 (show ZBTB24 Antibodies).
These findings suggest that Bif-1 (show ZBTB24 Antibodies) acts as a critical regulator of Atg9 (show ATG9A Antibodies) puncta formation presumably by mediating Golgi fission for autophagosome biogenesis during starvation.
GSK-3beta (show GSK3b Antibodies) promotes cell survival by modulating Bif-1 (show ZBTB24 Antibodies)-dependent autophagic response and cell death.
Double knockdown of endophilin B1 and Drp1 (show CRMP1 Antibodies) leads to a mitochondrial phenotype identical to that of the Drp1 (show CRMP1 Antibodies) single knockdown, a result consistent with Drp1 (show CRMP1 Antibodies) acting upstream of endophilin B1 in the maintenance of morphological dynamics of mitochondria.
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.
SH3-domain GRB2-like endophilin B1
, SH3 domain-containing GRB2-like protein B1
, Bax-interacting factor 1
, SH3-containing protein SH3GLB1
, protein phosphatase 1, regulatory subunit 70
, SH3-domain GRB2-like B1 (endophilin)
, SH3 domain GRB2-like protein B1