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anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Antibodies

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. Additionally we are shipping Sodium Channel, Nonvoltage-Gated 1 alpha Kits (12) and Sodium Channel, Nonvoltage-Gated 1 alpha Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCNN1A 6337 P37088
SCNN1A 20276 Q61180
SCNN1A 25122 P37089
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Top anti-Sodium Channel, Nonvoltage-Gated 1 alpha Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SCNN1A Antibody (Center) in WiDr cell line ly... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of SCNN1A Antibody (Center) (ABIN652752) in WiDr... Formalin-fixed and paraffin-embedded human lung carcinoma reacted with... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Mouse Rabbit FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$437.80
Details
Mouse Rabbit Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$440.00
Details
Mouse Rabbit Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$442.20
Details
Mouse Rabbit PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$443.30
Details
Mouse Rabbit Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$444.40
Details
Mouse Rabbit PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$445.50
Details
Mouse Rabbit APC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$445.50
Details

SCNN1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Sodium Channel, Nonvoltage-Gated 1 alpha Antibodies

  1. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486348 : Elias, Rafii, Rahman, Otulakowski, Cutz, OBrodovich: The role of alpha-, beta-, and gamma-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid. in American journal of physiology. Lung cellular and molecular physiology 2007 (PubMed)
    Show all 6 references for ABIN2486348

  2. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486349 : Kakizoe, Kitamura, Ko, Wakida, Maekawa, Miyoshi, Shiraishi, Adachi, Zhang, Masilamani, Tomita: Aberrant ENaC activation in Dahl salt-sensitive rats. in Journal of hypertension 2009 (PubMed)
    Show all 6 references for ABIN2486349

  3. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486347 : Gu: Effect of [Cl(-)]i on ENaC activity from mouse cortical collecting duct cells. in Journal of cellular physiology 2008 (PubMed)
    Show all 6 references for ABIN2486347

  4. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486342 : Bruns, Hu, Ahn, Sheng, Hughey, Kleyman: Multiple epithelial Na+ channel domains participate in subunit assembly. in American journal of physiology. Renal physiology 2003 (PubMed)
    Show all 6 references for ABIN2486342

  5. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486343 : Mauro, Guitard, Behne, Oda, Crumrine, Komuves, Rassner, Elias, Hummler: The ENaC channel is required for normal epidermal differentiation. in The Journal of investigative dermatology 2002 (PubMed)
    Show all 6 references for ABIN2486343

  6. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN2486341 : Dyka, May, Enz: Subunits of the epithelial sodium channel family are differentially expressed in the retina of mice with ocular hypertension. in Journal of neurochemistry 2005 (PubMed)
    Show all 6 references for ABIN2486341

  7. Human Polyclonal SCNN1A Primary Antibody for FACS, IF - ABIN652752 : Azad, Rauh, Vermeulen, Jaspers, Korbmacher, Boissier, Bassinet, Fichou, des Georges, Stanke, De Boeck, Dupont, Balascáková, Hjelte, Lebecque: Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. in Human mutation 2009 (PubMed)

More Antibodies against Sodium Channel, Nonvoltage-Gated 1 alpha Interaction Partners

Rabbit Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

Human Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. The transcriptional expression of alpha, beta, and gamma subunits of ENaC was elevated in nasal polyp compared to nasal mucosa

  2. The long isoform of alphaENaC forms the structural basis of a channel with different activity and regulation, which may not be easily distinguishable in native tissue, but may underlie sodium hyperabsorption and salt sensitive differences in humans.

  3. ENaC regulates miR (show MLXIP Antibodies)-101/miR (show MLXIP Antibodies)-199a-3p during embryo implantation with the involvement of CREB (show CREB1 Antibodies) phosphorylation.

  4. Five de novo mutations were identified in four genes (SCNN1A, KCNJ16 (show KCNJ16 Antibodies), KCNB2 (show KCNB2 Antibodies), and KCNT1 (show KCNT1 Antibodies)) in three Brugada syndrome patients

  5. ASIC1A (show ACCN2 Antibodies) and ENaCalpha form functional heterotrimers acting as ion channels.

  6. SCNN1A and SCNN1G SNPs may contribute to blood pressure changes over time in the Han Chinese population.

  7. Skin hydration status regulates sodium homeostasis and inflammatory pathways through the epithelial sodium channel (ENaC).

  8. Increased CFTR (show CFTR Antibodies) expression and decreased ENaC-alpha expression in the decidua of early abortion may relate with failure of early pregnancy.

  9. Cystic fibrosis (show S100A8 Antibodies)-like disease probably has an oligogenic origin, resulting from mutations in several genes, including CFTR (show CFTR Antibodies), SERPINA1 (show SERPINA1 Antibodies), and SCNN1 isoforms.

  10. In this study, authors found that miR (show MLXIP Antibodies)-125b inhibits hepatitis B virus expression in vitro by regulating SCNN1A expression.

Xenopus laevis Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

Mouse (Murine) Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. reducing ENaC expression in the connecting tubule induces clear pseudohypoaldosteronism type 1 symptoms during high dietary potassium loading

  2. The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 (show SLC12A1 Antibodies) and ENaCalpha in obstructive kidney disease, possibly via iNOS (show NOS2 Antibodies)-derived nitric oxide and BNP (show BNC2 Antibodies).

  3. PCSK9 (show PCSK9 Antibodies)(-/-) mice display normal sodium balance and blood pressure regulation despite an increase of cleaved alphaENaC under basal condition

  4. H-Ras (show HRAS Antibodies) mediates the inhibitory effect of epidermal growth factor (show EGF Antibodies) on the epithelial Na+ channel

  5. 17beta-estradiol attenuates LPS (show TLR4 Antibodies)-induced acute lung injury via PI3K/Akt (show AKT1 Antibodies)/SGK1 (show SGK1 Antibodies) mediated up-regulation of Scnn1a.

  6. ENaC regulates miR (show MLXIP Antibodies)-101/miR (show MLXIP Antibodies)-199a-3p during embryo implantation with the involvement of CREB (show CREB1 Antibodies) phosphorylation.

  7. Pendrin (show SLC26A4 Antibodies) gene ablation reduced ENaC-mediated Na(+) absorption by reducing channel open probability as well as by reducing channel density through changes in subunit total protein abundance and subcellular distribution.

  8. results are consistent with a role of alphaENaC in connecting tubule in rosiglitazone-induced fluid retention, which dovetails with the physiological relevance of ENaC in this segment

  9. In the absence of Na(+)-HCO3 (-) cotransporter (show SLC4A4 Antibodies) electrogenic 2 in the late distal tubule, acid-loaded mice exhibit disinhibition of ENaC-mediated Na(+) reabsorption, which results in Na(+) retention, K(+) wasting, and hypertension.

  10. sustained stimulatory effect of locally elevated norepinephrine on ENaC-mediated Na(+) absorption may contribute to the hypertensive effect of increased renal sympathetic activity

Guinea Pig Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. Different subunits of ENaC expressed in various cell regions of the cochlea and endolymphatic sac (show ADCY10 Antibodies) in distinct patterns may form the functional sodium channel to regulate the endolymph and maintain homeostasis in inner ear.

Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Antigen Profile

Protein Summary

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with SCNN1A

  • sodium channel, non-voltage-gated 1 alpha subunit (SCNN1A) antibody
  • sodium channel, nonvoltage-gated 1 alpha (SCNN1A) antibody
  • sodium channel, nonvoltage-gated 1 alpha (LOC100222046) antibody
  • epithelial sodium channel, alpha subunit (ALPHA-ENAC) antibody
  • sodium channel, non-voltage-gated 1 alpha subunit (scnn1a) antibody
  • sodium channel, nonvoltage-gated 1, delta (SCNN1D) antibody
  • sodium channel, nonvoltage-gated 1 alpha (Scnn1a) antibody
  • alphaxENaC antibody
  • besc2 antibody
  • ENAC antibody
  • enaca antibody
  • ENaCalpha antibody
  • mENaC antibody
  • SCNEA antibody
  • Scnn1 antibody
  • SCNN1A antibody

Protein level used designations for SCNN1A

alpha-subunit renal epithelial sodium channel , amiloride-sensitive sodium channel subunit alpha , sodium channel, nonvoltage-gated 1 alpha , alpha ENaC , epithelial sodium channel alpha subunit , epithelium sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, alpha , amiloride-sensitive sodium channel alpha subunit , SCNEA , alpha-NaCH , epithelial Na(+) channel subunit alpha , epithelial sodium channel ENaC alpha subunit , nonvoltage-gated sodium channel 1 subunit alpha , alpha ENaC-2 , alpha-ENaC , amiloride-sensitive epithelial sodium channel alpha subunit , amiloride-sensitive sodium channel subunit alpha 2 , nasal epithelial sodium channel alpha subunit , alpha cENaC 431 , amiloride-sensitve epithelial sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, delta , ENaC alpha , amiloride-sensitive epithelial sodium channel , sodium channel, nonvoltage-gated, type I, alpha polypeptide , sodium channel, nonvoltage-gated, type I, alpha

GENE ID SPECIES
396608 Sus scrofa
403650 Canis lupus familiaris
443488 Ovis aries
451776 Pan troglodytes
100222046 Taeniopygia guttata
100484947 Ailuropoda melanoleuca
100014763 Monodelphis domestica
100009488 Oryctolagus cuniculus
6337 Homo sapiens
282348 Bos taurus
396050 Gallus gallus
397811 Xenopus laevis
428184 Gallus gallus
20276 Mus musculus
25122 Rattus norvegicus
100135613 Cavia porcellus
Selected quality suppliers for anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Antibodies
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