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TFAP2B encodes a member of the AP-2 family of transcription factors. Additionally we are shipping TFAP2B Proteins (6) and TFAP2B Kits (4) and many more products for this protein.
Showing 10 out of 94 products:
Human Monoclonal TFAP2B Primary Antibody for WB - ABIN394169
Hotta, Nakamura, Nakamura, Matsuo, Nakata, Kamohara, Miyatake, Kotani, Komatsu, Itoh, Mineo, Wada, Yoneda, Nakajima, Funahashi, Miyazaki, Tokunaga, Kawamoto, Masuzaki, Ueno, Hamaguchi, Tanaka, Yamada, Hanafusa, Oikawa, Yoshimatsu, Nakao, Sakata, Matsuzawa: Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population. in Journal of human genetics 2010
Show all 5 references for ABIN394169
Human Polyclonal TFAP2B Primary Antibody for ELISA, WB - ABIN563152
Bassett, Pontoriero, Feng, Marquardt, Fini, Williams, West-Mays: Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development. in Molecular and cellular biology 2007
Chicken Polyclonal TFAP2B Primary Antibody for WB - ABIN2774206
Hensch, Wargelius, Herold, Strobel, Oreland, Brocke: Electrophysiological and behavioral correlates of polymorphisms in the transcription factor AP-2beta coding gene. in Neuroscience letters 2008
Chicken Polyclonal TFAP2B Primary Antibody for WB - ABIN2777940
Mishra, Keyel, Edeling, Dupin, Owen, Traub: Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein. in The Journal of biological chemistry 2005
AP-2beta up-regulates the transcription of the CRYAB (show CRYAB Antibodies) gene through stabilizing p53 (show TUBB Antibodies).
CVAK104 (show SCYL2 Antibodies) binds ATP and functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosphorylation and phosphorylating the beta2-adaptin (show AP2B1 Antibodies) subunit of AP2 (show TFAP2A Antibodies)
tfap2b and its close relative, tfap2a (show TFAP2A Antibodies), play redundant roles in the ectoderm to control skeletogenesis of neural crest cells
the Tfap2a (show TFAP2A Antibodies) and Tfap2b transcription factors were identified as two major downstream effectors of Ptf1a (show PTF1A Antibodies).
critical roles for AP-2 (show TFAP2A Antibodies) activity in retinogenesis, delineating the overlapping expression patterns of Tcfap2a (show TFAP2A Antibodies), Tcfap2b, and Tcfap2c in the neural retina, and revealing a redundant requirement for Tcfap2a (show TFAP2A Antibodies) and Tcfap2b in horizontal and amacrine cell development
Tfap2b is associated with the development and remodeling of mouse ductus arteriosus and limb patterning.
PKD (show PRKD1 Antibodies) is thus a common modulator of the DNA binding activity of AP-2alpha (show TFAP2A Antibodies) and AP-2beta through their phosphorylation for negative regulation of the ABCA1 (show ABCA1 Antibodies) and adiponectin (show ADIPOQ Antibodies) genes expression, respectively.
postprandial activation of PKCmicro plays a role in disordered postprandial adipocytokine expression through AP-2beta.
Whereas AP-2alpha (show TFAP2A Antibodies)/beta transcription factors are in vivo not required for the onset or maintenance of noradrenergic differentiation, their essential survival functions are demonstrated for sympathetic progenitors and noradrenergic neurons.
Data suggest that AP-2beta plays critical roles in the epinephrine phenotype and maturation of adrenal chromaffin cells.
Tfap2beta, Et-1 (show EDN1 Antibodies), and Hif2alpha (show EPAS1 Antibodies) act in a transcriptional network during ductal smooth muscle development. Disruption of this pathway may contribute to patent ductus arteriosus by affecting development of smooth muscle in the ductus arteriosus.
AP-2beta transcriptional factor is a unique regulator of IRS-1 (show IRS1 Antibodies) and a candidate gene for insulin (show INS Antibodies) resistance.
AP-2beta is a candidate gene for producing adipocyte hypertrophy and may relate to the abnormal characteristics of adipocytes observed in obesity.
results suggest that TFAP2B is playing a vital role in retaining retinoic acid responsiveness and mediating noradrenergic neuronal differentiation in neuroblastoma (show ARHGEF16 Antibodies).
TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK (show EPHB2 Antibodies) and VEGF (show VEGFA Antibodies)/PEDF (show SERPINF1 Antibodies) signaling.
The AP-2beta polymorphism significantly influenced cognitive performance, whereas the MAOA (show MAOA Antibodies) and COMT (show COMT Antibodies) polymorphisms did not.
A haploinsufficiency effect of TFAP2B could be involved in familial isolated patent ductus arteriosus.
TFAP2B rs987237 and dietary protein/carbohydrate interacted to modify weight maintenance.
genomic GATA4 (show GATA4 Antibodies) and TFAP2B missense mutations may be associated with nonfamilial congenital heart disease with diverse clinical phenotypes in patients with congenital heart disease from southern China
Under energy restriction, TFAP2B may modify the effect of dietary fat intake on weight loss and waist reduction
The findings suggest the lack of involvement of known mutations of TFAP2B with syndromic or nonsyndromic CHDs in Mysore patients
TFAP2B mutation should be considered a risk factor for isolated PDA. However, the detailed genetic mechanism underlying nonsyndromic the PDA-causing TFAP2B mutation is yet to be elucidated.
This study supports a role of the SLC6A4 (show SLC6A4 Antibodies), DRD4 (show DRD4 Antibodies) and TFAP2B genes in the temperament, including a gene-gene interaction between SLC6A4 (show SLC6A4 Antibodies) and TFAP2B. It also provides evidence about an effect of the TFAP2B polymorphism in TFAP2B gene transcription.
Expression of TFAP2beta and TFAP2gamma (show TFAP2C Antibodies) genes in Xenopus laevis.
LH and insulin (show INS Antibodies) stimulate transcription of -976/+31 bp 5 (show HSPD1 Antibodies)'-upstream cis (show CISH Antibodies)-acting region of porcine CYP17 (show CYP17A1 Antibodies) gene. Maximal transcriptional responsiveness requires proximal Sp1 (show SP1 Antibodies) and AP-2-like (show TFAP2D Antibodies) sequences -193 to -180 bp 5 (show HSPD1 Antibodies)' upstream of transcriptional start site.
Data demonstrates the colocalization of MARK with AP-2 and clathrin, as well as other MARK-interacting proteins such as PAK5.
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
, beta adaptin drosophila 1
, transcription factor AP-2 beta
, AP2 transcription factor
, activating enhancer-binding protein 2 beta
, transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
, transcription factor AP-2-beta
, activating enhancer-binding protein 2-beta
, activating enhancer binding protein 2 beta