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VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) ELISA Kits

The protein encoded by VAPB is a type IV membrane protein found in plasma and intracellular vesicle membranes. Additionally we are shipping VAPB Antibodies (78) and VAPB Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
VAPB 9217 O95292
VAPB 60431 Q9Z269
VAPB 56491  
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Top VAPB ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 21 to 31 Days
$755.70
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
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$875.60
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Pig
96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for VAPB Interaction Partners

Human VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) interaction partners

  1. Effects of the combined absence of VAPA (show VAPA ELISA Kits) and VAPB in human cells were studied; cells lacking VAP (show F10 ELISA Kits) accumulate high levels of PI4P, actin comets, and trans-Golgi proteins on endosomes. Such defects are mimicked by downregulation of OSBP (show OSBP ELISA Kits), a VAP (show F10 ELISA Kits) interactor and PI4P transporter that participates in VAP (show F10 ELISA Kits)-dependent endoplasmic reticulum-endosomes tethers.

  2. this is the first study to report Amyotrophic lateral sclerosis caused by a VAPB mutation in a Chinese population.

  3. Our work revealed that VAP-A/B knockdown impaired the processing and secretion of PAUF, which is one of the cargo proteins of carriers of the trans-Golgi network to the cell surface.

  4. Heterozygous P56S Vapb knock-in mice show mild age-dependent defects in motor behaviors as characteristic features of the disease. The homozygous P56S Vapb knock-in mice show more severe defects compared with heterozygous mice reflecting the dominant and dose-dependent effects of P56S mutation.

  5. VAPB inhibited the degradation of DeltaF508-CFTR in the ER through interactions with the RMA1-Derlin-BAP31-VCP pathway.

  6. Study characterizes the human VAPB-HCV NS5B interaction and reveals that NS5B C-linker is intrinsically disordered in solution but capable of binding the human VAPB-MSP (show MSMB ELISA Kits) domain which overlaps with those for binding HCV NS5A and human Eph (show EPHA1 ELISA Kits) receptors.

  7. The VAPB and its interacting partners cooperatively regulate protein trafficking through the ERGIC by modulating PtdIns4P levels.

  8. results suggest that the binding of vesicle-associated membrane protein-associated protein B(VAP-B) to Rab3 GTPase activating protein 1(RAB3GAP1 (show RAB3GAP1 ELISA Kits)) is implicated in the regulation of nuclear envelope formation through ER-Golgi intermediate compartment

  9. P56S-VAPB was found to suppress adipocyte differentiation by promoting the activation of the ATF4 (show ATF4 ELISA Kits)-CHOP (show DDIT3 ELISA Kits) pathway

  10. The repertoire of VAPB interactors is more diverse than previously anticipated and link VAPB to the function of ATPase (show DNAH8 ELISA Kits) complexes such as p97 (show EIF4G2 ELISA Kits)/FAF1 (show FAF1 ELISA Kits) and ASNA1 (show ASNA1 ELISA Kits)/transmembrane-domain recognition complex.

Mouse (Murine) VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) interaction partners

  1. To identify pathological defects in animals expressing the P56S mutant VAPB protein at physiological levels in the appropriate tissues, we have generated Vapb knock-in mice

  2. The disruption of the IRE1 (show ERN1 ELISA Kits)-XBP1 (show XBP1 ELISA Kits) pathway is a cause for the reduced myotube formation in P56S-VAPB-mutation expressing cells.

  3. Vapb knock-out mice exhibit abnormal muscular triacylglycerol levels and FoxO (show FOXO3 ELISA Kits) target gene transcriptional responses to fasting and refeeding

  4. Mice knocked-out for Vapb showed mild motor deficits after 18 months of age.

  5. VapB positively regulates RANKL (show TNFSF11 ELISA Kits)-mediated osteoclastogenesis via PLCgamma2 (show PLCG2 ELISA Kits)-Ca(2 (show CA2 ELISA Kits)+)-NFAT (show NFATC1 ELISA Kits) signaling

  6. Co-expression of mutant protein-associated protein B (show LEPREL2 ELISA Kits) (VAPB) enhances the transactive response DNA-binding protein (show HSF4 ELISA Kits)-43 (TDP-43 (show TARDBP ELISA Kits))-induced motor neuronal cell death while that of wild type-VAPB attenuates it.

  7. Adeno (show ADORA2A ELISA Kits)-associated viral-mediated over-expression of both wild-type and mutated form of human VAPB selectively induces death of primary motor neurons, albeit with different kinetics.

  8. However, VAPBP56S but not VAPBwt transgenic mice develop cytoplasmic TDP-43 (show TARDBP ELISA Kits) accumulations within spinal cord motor neurons that were first detected at 18 months of age.

  9. The total loss of VAPB function in unfolded protein response, induced by one P56S mutant allele, may contribute to the development of P56SVAPB- induced amyotrophic lateral sclerosis.

VAPB Antigen Profile

Antigen Summary

The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.

Gene names and symbols associated with VAPB

  • vesicle-associated membrane protein-associated protein B/C (Tsp_07972) antibody
  • VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB) antibody
  • VAMP-associated protein B/C (LOC788595) antibody
  • VAMP-associated protein B/C (LOC100350714) antibody
  • VAMP (vesicle-associated membrane protein)-associated protein B and C (Vapb) antibody
  • vesicle-associated membrane protein, associated protein B and C (Vapb) antibody
  • AI225786 antibody
  • AI840687 antibody
  • AI848259 antibody
  • ALS8 antibody
  • D2Abb2e antibody
  • R75548 antibody
  • VAMP-B antibody
  • Vamp33b antibody
  • VAP-B antibody
  • VAP33b antibody

Protein level used designations for VAPB

vesicle-associated membrane protein-associated protein B/C , VAMP (vesicle-associated membrane protein)-associated protein B and C , VAMP-associated protein B/C , VAMP-associated 33 kDa protein , VAMP-B , VAMP-associated protein B , VAP-B , vesicle-associated membrane protein-associated protein B , vesicle-associated membrane protein, associated protein B and C , VAMP-associated protein 33b

GENE ID SPECIES
10906529 Trichinella spiralis
469984 Pan troglodytes
788595 Bos taurus
100350714 Oryctolagus cuniculus
9217 Homo sapiens
419317 Gallus gallus
100144536 Sus scrofa
326580 Bos taurus
60431 Rattus norvegicus
56491 Mus musculus
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