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VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) ELISA Kits

The protein encoded by VAPB is a type IV membrane protein found in plasma and intracellular vesicle membranes. Additionally we are shipping VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C Antibodies (67) and VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human VAPB VAPB 9217 O95292
Anti-Rat VAPB VAPB 60431 Q9Z269
Anti-Mouse VAPB VAPB 56491  
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More ELISA Kits for VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C Interaction Partners

Human VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) interaction partners

  1. VAPB inhibited the degradation of DeltaF508-CFTR in the ER through interactions with the RMA1-Derlin-BAP31-VCP pathway.

  2. Study characterizes the human VAPB-HCV NS5B interaction and reveals that NS5B C-linker is intrinsically disordered in solution but capable of binding the human VAPB-MSP (show MSMB ELISA Kits) domain which overlaps with those for binding HCV NS5A and human Eph (show EPHA1 ELISA Kits) receptors.

  3. The VAPB and its interacting partners cooperatively regulate protein trafficking through the ERGIC by modulating PtdIns4P levels.

  4. results suggest that the binding of vesicle-associated membrane protein-associated protein B(VAP-B) to Rab3 GTPase activating protein 1(RAB3GAP1 (show RAB3GAP1 ELISA Kits)) is implicated in the regulation of nuclear envelope formation through ER-Golgi intermediate compartment

  5. P56S-VAPB was found to suppress adipocyte differentiation by promoting the activation of the ATF4 (show ATF4 ELISA Kits)-CHOP (show DDIT3 ELISA Kits) pathway

  6. The repertoire of VAPB interactors is more diverse than previously anticipated and link VAPB to the function of ATPase (show DNAH8 ELISA Kits) complexes such as p97 (show EIF4G2 ELISA Kits)/FAF1 (show FAF1 ELISA Kits) and ASNA1 (show ASNA1 ELISA Kits)/transmembrane-domain recognition complex.

  7. In patients with familial or sporadic amyotrophic lateral sclerosis (ALS (show IGFALS ELISA Kits)) from Portugal, Iceland and Sweden no association is found with disease and VAMP-associated protein type B (VAPB) mutations.

  8. Findings provide new pathophysiological mechanisms of P56S VAPB that differentially affect the function and survival of corticospinal and spinal motor neurons in familial amyotrophic lateral sclerosis 8.

  9. Partial or complete loss of VAPB function leads to motor deficit but is unable to trigger a full-blown amyotrophic lateral sclerosis phenotype.

  10. this discovery provides a mechanism for ALS (show IGFALS ELISA Kits)-causing VAPB mutants/variants to gain novel functions such as to mediate ER structure before significant accumulation of aggregates occurs.

Mouse (Murine) VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) interaction partners

  1. The disruption of the IRE1 (show ERN1 ELISA Kits)-XBP1 (show XBP1 ELISA Kits) pathway is a cause for the reduced myotube formation in P56S-VAPB-mutation expressing cells.

  2. Vapb knock-out mice exhibit abnormal muscular triacylglycerol levels and FoxO (show FOXO3 ELISA Kits) target gene transcriptional responses to fasting and refeeding

  3. Mice knocked-out for Vapb showed mild motor deficits after 18 months of age.

  4. VapB positively regulates RANKL (show TNFSF11 ELISA Kits)-mediated osteoclastogenesis via PLCgamma2 (show PLCG2 ELISA Kits)-Ca(2 (show CA2 ELISA Kits)+)-NFAT (show NFATC1 ELISA Kits) signaling

  5. Co-expression of mutant protein-associated protein B (show LEPREL2 ELISA Kits) (VAPB) enhances the transactive response DNA-binding protein (show HSF4 ELISA Kits)-43 (TDP-43 (show TARDBP ELISA Kits))-induced motor neuronal cell death while that of wild type-VAPB attenuates it.

  6. Adeno (show ADORA2A ELISA Kits)-associated viral-mediated over-expression of both wild-type and mutated form of human VAPB selectively induces death of primary motor neurons, albeit with different kinetics.

  7. However, VAPBP56S but not VAPBwt transgenic mice develop cytoplasmic TDP-43 (show TARDBP ELISA Kits) accumulations within spinal cord motor neurons that were first detected at 18 months of age.

  8. The total loss of VAPB function in unfolded protein response, induced by one P56S mutant allele, may contribute to the development of P56SVAPB- induced amyotrophic lateral sclerosis.

VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB) Antigen Profile

Antigen Summary

The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.

Gene names and symbols associated with VAPB

  • vesicle-associated membrane protein-associated protein B/C (Tsp_07972) antibody
  • VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB) antibody
  • VAMP-associated protein B/C (LOC788595) antibody
  • VAMP-associated protein B/C (LOC100350714) antibody
  • VAMP (vesicle-associated membrane protein)-associated protein B and C (Vapb) antibody
  • vesicle-associated membrane protein, associated protein B and C (Vapb) antibody
  • AI225786 antibody
  • AI840687 antibody
  • AI848259 antibody
  • ALS8 antibody
  • D2Abb2e antibody
  • R75548 antibody
  • VAMP-B antibody
  • Vamp33b antibody
  • VAP-B antibody
  • VAP33b antibody

Protein level used designations for VAPB

vesicle-associated membrane protein-associated protein B/C , VAMP (vesicle-associated membrane protein)-associated protein B and C , VAMP-associated protein B/C , VAMP-associated 33 kDa protein , VAMP-B , VAMP-associated protein B , VAP-B , vesicle-associated membrane protein-associated protein B , vesicle-associated membrane protein, associated protein B and C , VAMP-associated protein 33b

GENE ID SPECIES
10906529 Trichinella spiralis
469984 Pan troglodytes
788595 Bos taurus
100350714 Oryctolagus cuniculus
9217 Homo sapiens
419317 Gallus gallus
100144536 Sus scrofa
326580 Bos taurus
60431 Rattus norvegicus
56491 Mus musculus
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