Apotosis Activator 2
Quick Overview for Apotosis Activator 2 (ABIN924978)
Application
Apoptosis Induction (AI), Cell Culture (CC)
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Purity
- > 98 % by NMR analysis
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Chemical Name
- 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
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Formula
- C15H9NO2Cl2
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Solubility
- Soluble in DMSO or 100% ethanol
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Comment
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Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome and triggering caspase-9 activation resulting in activated caspase-3. Shows a stronger selectivity for cancer cells than for normal cell lines. Acts in a similar fashion as apoptosis inducer alpha- (trichloromethyl)-4-pyridineethanol (PETCM).
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Restrictions
- For Research Use only
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Format
- Solid
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Storage
- 4 °C
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Molecular Weight
- 306.1 g/mol
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