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Browse our anti-Acetyl-CoA Carboxylase beta (ACACB) Antibodies

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anti-Acetyl-CoA Carboxylase beta Antibodies (ACACB)
On are 51 Acetyl-CoA Carboxylase beta (ACACB) Antibodies from 12 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 56 Acetyl-CoA Carboxylase beta products are currently listed.
Acc2, Accb, acetyl-CoA carboxylase 2, AI597064, AW743042, F15C21.2, F15C21_2, HACC275
list all antibodies Gene Name GeneID UniProt
ACACB 32 O00763
ACACB 116719  
ACACB 100705  

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Most Popular Reactivities for anti-Acetyl-CoA Carboxylase beta (ACACB) Antibodies

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anti-Human Acetyl-CoA Carboxylase beta Antibodies:

anti-Rat (Rattus) Acetyl-CoA Carboxylase beta Antibodies:

anti-Mouse (Murine) Acetyl-CoA Carboxylase beta Antibodies:

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Top referenced anti-Acetyl-CoA Carboxylase beta Antibodies

  1. Human Polyclonal Acetyl-CoA Carboxylase beta Primary Antibody for ELISA, WB - ABIN190803 : Reznick, Zong, Li, Morino, Moore, Yu, Liu, Dong, Mustard, Hawley, Befroy, Pypaert, Hardie, Young, Shulman: Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. in Cell metabolism 2007 (PubMed)

  2. Human Polyclonal Acetyl-CoA Carboxylase beta Primary Antibody for IHC, IHC (p) - ABIN4277614 : Ma, Murea, Snipes, Marinelarena, Krüger, Hicks, Langberg, Bostrom, Cooke, Suzuki, Babazono, Uzu, Tang, Mondal, Sharma, Kobes, Antinozzi, Davis, Das, Rasouli, Kern, Shores, Rudel, Blüher, Stumvoll et al.: An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects. ... in PLoS ONE 2013 (PubMed)

More Antibodies against Acetyl-CoA Carboxylase beta Interaction Partners

Human Acetyl-CoA Carboxylase beta (ACACB) interaction partners

  1. A significant association exists of ACACB gene polymorphism and diabetic nephropathy among Caucasian patients with diabetes.

  2. Our meta-analysis supports that the apolipoprotein E (show APOE Antibodies) epsilon2 allele and acetyl-CoA carboxylase beta rs2268388 C>T might act as promotion factors of nephropathy in type 2 diabetes.

  3. The knockdown of ACC2 reduced palmitic acid -induced autophagy and thus protects the cells from palmitic acid - induced lipotoxicity with attenuated lipid accumulation and rescued cell viability.

  4. These data support a role for ACACB in obesity and potential roles for altered lipid metabolism in susceptibility to diabetic nephropathy.

  5. TT genotypes of ACACB gene (rs2268388) and CC genotype of AGTR1 (show AGTR1 Antibodies) gene (rs5186) confers the risk of diabetic nephropathy in Asian Indian patients with T2DM.

  6. A gene polymorphism in acetyl-coenzyme A carboxylase beta may be associated with the C-reactive protein (show CRP Antibodies) level in a prediabetic and diabetic population.

  7. In conclusion, common polymorphisms of ACACB gene are associated with obesity and, independently, with type 2 diabetes in postmenopausal women

  8. Common variants within the ACACB locus appear to regulate adipose gene expression

  9. The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes.

  10. Acetyl-CoA carboxylase beta (ACC2) plays a key role in fatty acid synthesis and oxidation pathways.

Mouse (Murine) Acetyl-CoA Carboxylase beta (ACACB) interaction partners

  1. These results suggest that ACC2 is dispensable for CD8 (show CD8A Antibodies)+ T cell responses.

  2. AMPK (show PRKAA1 Antibodies)-dependent inactivation of ACC (show ACACA Antibodies) is not essential for the control of myocardial FAO and subsequent cardiac function during a variety of conditions involving AMPK (show PRKAA1 Antibodies)-independent and AMPK (show PRKAA1 Antibodies)-dependent metabolic adaptations.

  3. Data show that acetyl CoA carboxylase 2 ACC2 deletion led to a significant reduction in cardiac malonyl CoA levels.

  4. Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db (show LEPR Antibodies) mice.

  5. the ACC2 deletion protects against fatty liver, despite increased de novo lipogenesis and a diet that induces obesity, fatty liver, and diabetes.

  6. Acc2 does not have a major role in regulating body weight, fat mass, or food intake

  7. ACC2 plays an essential role in controlling fatty acid oxidation and is a potential target in therapy against obesity and related diseases.

  8. Fatty acid oxidation in the adipocytes of Acc2-/- mutant mice, combined with a higher level of glucose oxidation and a higher rate of lipolysis, are major factors leading to efficient maintenance of insulin (show INS Antibodies) sensitivity and leaner (show CACNA1A Antibodies) Acc2-/- mutant mice.

  9. Acc2(-/-) mice were protected from fat-induced peripheral and hepatic insulin (show INS Antibodies) resistance.

  10. Report reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice.

Acetyl-CoA Carboxylase beta (ACACB) Antigen Profile

Antigen Summary

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Alternative names and synonyms associated with Acetyl-CoA Carboxylase beta (ACACB)

  • acetyl-CoA carboxylase 2 (ACC2) antibody
  • acetyl-CoA carboxylase beta (ACACB) antibody
  • acetyl-CoA carboxylase beta (Acacb) antibody
  • acetyl-Coenzyme A carboxylase beta (Acacb) antibody
  • Acc2 antibody
  • Accb antibody
  • acetyl-CoA carboxylase 2 antibody
  • AI597064 antibody
  • AW743042 antibody
  • F15C21.2 antibody
  • F15C21_2 antibody
  • HACC275 antibody

Protein level used designations for ACACB

ACC-beta , acetyl-CoA carboxylase 2 , acetyl-Coenzyme A carboxylase beta , acetyl-Coenzyme A carboxylase 2

840522 Arabidopsis thaliana
32 Homo sapiens
116719 Rattus norvegicus
100705 Mus musculus
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