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Acetyl-CoA Carboxylase beta antibody (ACACB) (pSer220) (Biotin) Primary Antibody

ACACB Reactivity: Human ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700093
$419.10
Plus shipping costs $45.00
100 μL
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  • Target
    Acetyl-CoA Carboxylase beta (ACACB)
    Binding Specificity
    • 14
    • 9
    • 1
    • 1
    • 1
    • 1
    pSer220
    Reactivity
    • 33
    • 9
    • 2
    • 1
    Human
    Host
    • 24
    • 10
    • 1
    Rabbit
    Clonality
    • 34
    • 1
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Acetyl-CoA Carboxylase beta antibody is conjugated to Biotin
    Application
    • 16
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Target
    Acetyl-CoA Carboxylase beta (ACACB)
    Alternative Name
    Acetyl Coenzyme A Carboxylase beta (ACACB Antibody Abstract)
    Synonyms
    F15C21.2, F15C21_2, acetyl-CoA carboxylase 2, ACC2, ACCB, HACC275, Acc2, AI597064, AW743042, Accb, acetyl-CoA carboxylase 2, acetyl-CoA carboxylase beta, acetyl-Coenzyme A carboxylase beta, ACC2, ACACB, Acacb
    Background

    Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

    Subcellular location: Cell membrane

    Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220,

    Pathways
    AMPK Signaling, Ribonucleoside Biosynthetic Process
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