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Sad1 and UNC84 Domain Containing 1 (SUN1) antibody

Details for Product No. ABIN1042680, Supplier: Log in to see
Antigen
  • UNC84A
  • 4632417G13Rik
  • 5730434D03Rik
  • Unc84a
  • mKIAA0810
Reactivity
Human
15
3
3
1
Host
Rabbit
10
5
Conjugate
Un-conjugated
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
15
5
1
1
Supplier
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Immunogen GST-Sun 1 peptide
Alternative Name SUN1 (SUN1 Antibody Abstract)
Background Synonyms:
Protein unc-84 homolog A antibody,Sad1/unc 84 protein like 1 antibody,Sad1/unc-84 protein-like 1 antibody,Sun domain-containing protein 1 antibody,Sun1 antibody,SUN1_HUMAN antibody,UNC 84 homolog A (C elegans) antibody,UNC 84A antibody,UNC84 A antibody,UNC84 antibodyNC84 homolog A (C elegans) antibody
UniProt O94901
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Pathways
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try between 1:500-1:2000
Comment

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs)

Restrictions For Research Use only
Format Liquid
Buffer Serum containing 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
 image for anti-Sad1 and UNC84 Domain Containing 1 (SUN1) antibody (ABIN1042680) anti-Sad1 and UNC84 Domain Containing 1 (SUN1) antibody
Product cited in: Hodzic, Yeater, Bengtsson et al.: "Sun2 is a novel mammalian inner nuclear membrane protein." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25805-12, 2004 (PubMed).