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Details for Product No. ABIN1042680

Sad1 and UNC84 Domain Containing 1 (SUN1) antibody

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Antigen
Synonyms UNC84A, 4632417G13Rik, 5730434D03Rik, Unc84a, mKIAA0810
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Application
»Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Pubmed 1 reference available
Catalog no. ABIN1042680
Quantity 0.1 mL
Price
576.05 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 6 Business Days
Immunogen GST-Sun 1 peptide
Characteristics Rabbit Anti-SUN1
Purification Serum
Alternative Name SUN1
Gene ID 23353
OMIM 607723
UniProt O94901
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try between 1:500-1:2000
Comment

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs)

Restrictions For Research Use only
Format Liquid
Buffer Serum containing 0.1% sodium azide
Preservative Sodium azide
Product cited in: Hodzic, Yeater, Bengtsson et al.: "Sun2 is a novel mammalian inner nuclear membrane protein." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25805-12, 2004 (PubMed).

Alternatives for antigen "Sad1 and UNC84 Domain Containing 1 (SUN1)", type "Antibodies"
Hosts (4), (4)
Reactivities (7), (1), (1), (1)
Applications (8), (2), (2), (1), (1)
Epitopes (3), (1)
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