Pepsinogen II (PGII) antibody

Antigen: Pepsinogen II (PGII)

Clonality: Monoclonal (L10CC10)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Catalog no.: ABIN108410

Additional Information

Alternative name: Pepsinogen II

Immunogen: Pepsinogen II purified from human tissue was used as an immunogen.

Format: Purified

Isotype: IgG1

Clone: L10CC10

Description: Monoclonal Antibody to Human Gastric Biomarkers

Specificity: The antibody is specific to human pepsinogen II with no crossreactivity to human pepsinogen I.

Application Details

Application Notes: Reactivity with paraffin sections

Storage: This product should be stored at +2 C to +8 C

Research Area: Proteases

Restrictions: For Research Use only

Publications

Varis K, Samloff IM, Ihamaki T et al.: "An appraisal of tests for severe atrophic gastritis in relatives of patients with pernicious anemia." in: Dig Dis Sci, Vol. 24, Issue 3, pp. 187-91, 1979 (PubMed).

Farinati F, Di Mario F, Plebani M et al.: "Pepsinogen A/pepsinogen C or pepsinogen A multiplied by gastrin in the diagnosis of gastric cancer?" in: Ital J Gastroenterol, Vol. 23, Issue 4, pp. 194-6, 1991 (PubMed).

Sipponen P, Kekki M, Haapakoski J et al.: "Gastric cancer risk in chronic atrophic gastritis: statistical calculations of cross-sectional data." in: Int J Cancer, Vol. 35, Issue 2, pp. 173-7, 1985 (PubMed).

Kikuchi S, Wada O, Miki K et al.: "Serum pepsinogen as a new marker for gastric carcinoma among young adults. Research Group on Prevention of Gastric Carcinoma among Young Adults." in: Cancer, Vol. 73, Issue 11, pp. 2695-702, 1994 (PubMed).

Hattori Y, Tashiro H, Kawamoto T et al.: "Sensitivity and specificity of mass screening for gastric cancer using the measurment of serum pepsinogens." in: Jpn J Cancer Res, Vol. 86, Issue 12, pp. 1210-5, 1995 (PubMed).

Yoshihara M, Sumii K, Haruma K et al.: "The usefulness of gastric mass screening using serum pepsinogen levels compared with photofluorography." in: Hiroshima J Med Sci, Vol. 46, Issue 2, pp. 81-6, 1997 (PubMed).

Aoki K, Misumi J, Kimura T et al.: "Evaluation of cutoff levels for screening of gastric cancer using serum pepsinogens and distributions of levels of serum pepsinogen I, II and of PG I/PG II ratios in a gastric cancer case-control study." in: J Epidemiol, Vol. 7, Issue 3, pp. 143-51, 1997 (PubMed).

Yoshihara M, Sumii K, Haruma K et al.: "Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects." in: Am J Gastroenterol, Vol. 93, Issue 7, pp. 1090-6, 1998 (PubMed).