The Rabbit Polyclonal anti-Stromal Cell Derived Factor antibody is suitable to detect Stromal Cell Derived Factor in samples from Mouse. It has been validated for IP, IHC and WB.
Quick Overview for Stromal Cell Derived Factor antibody (ABIN110540)
Target
Stromal Cell Derived Factor
Reactivity
Mouse
Host
Rabbit
Clonality
Polyclonal
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Restrictions
For Research Use only
Format
Lyophilized
Storage
4 °C
Target
Stromal Cell Derived Factor
Alternative Name
SDF-1 (Stromal Cell-Derived Factor, PBSF)
Background
SDF-1a (stromal cell-derived factor-a)1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects ofB-cell lymphopoiesis and bone marrow myelopoiesis3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.