IL-6 Receptor antibody

Catalog No. ABIN1105829

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Specificity: This antibody recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein.Aff. Const.:Kd: 1.22 mM

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: gp80 transfected CHO cell line

Clone: B-R6

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126 / IL6R (IL6R Products)

Background: Synonyms: IL-6R 1, IL-6R-alpha, IL6 Receptor alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80

Gene ID: 3570

NCBI Accession: NP_000556

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints