»
Antibodies
»
anti-Cardiac Troponin I (TNNI3) antibody
Cardiac Troponin I (TNNI3) antibody
| Antigen |
|
| Synonyms |
CMH7, RCM1, cTnI, CMD2A, TNNC1, MGC116817, Tn1, LOC397803, TnIc, ctnIc, cmh7, ctni, tnnc1, TNNI3 |
| Clonality |
Monoclonal (C5) |
|
Host
|
|
|
Reactivity
|
 Alternatives Amphibian, Cow (Bovine), Chicken, Fish, Human, Mouse (Murine), Rabbit
Human (50), Cow (Bovine) (8), Rabbit (8), Dog (Canine) (7), Cat (Feline) (5), Goat (5), Mouse (Murine) (5), Pig (Porcine) (5), Rat (Rattus) (5), Chicken (2), Fish (2), Mammalian (2), Amphibian (1), Monkey (1)
|
|
Application
|
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
|
| Catalog no. |
ABIN112500 |
| Quantity |
0.2 mg (1.0 mg/ml) (Variants) |
| Price |
290.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: TNNI3, TNNC1
|
|
Alternative name
|
Cardiac Troponin I (+ skeletal)
|
|
Swiss-Prot
|
P19429
|
|
Immunogen
|
Free Troponin I from human heart
|
|
Isotype
|
IgG2b (Matching secondary antibodies)
|
|
Clone
|
C5
|
|
Description
|
Troponin I is 1 of 3 subunits that constitute the troponin complex which plays an importantrole in the regulation of skeletal and cardiac muscle contraction. It is presented in cardiactissue by a single isoform with a molecular weight of 29 kDa and is known as a specificmarker for cardiac tissue damage.
|
|
Specificity
|
Reacts with Troponin I from cardiac and skeletal muscle. The antibody is specific for anepitope between amino acids 186-192 of cardiac Troponin I. It is reactive with helix cardiacand skeletal isoforms. Species: Human, Bovine, Goat, Pig, Cat, Rabbit, Rat, Mouse, Chicken, Fish and Dog. Others not tested.
|
|
Application Notes
|
Suitable for use in ELISA and Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.0 mg/ml
|
|
Buffer
|
PBS, pH 7.2 containing 0.09% Sodium Azide as preservative.
|
|
Storage
|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
|
|
Research Area
|
Serum/Plasma Proteins
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Cardiac Troponin I (TNNI3)", type "Antibodies"
|
Hosts
|
Mouse (45), Goat (4), Rabbit (3)
|
|
Reactivities
|
Human (50), Cow (Bovine) (8), Rabbit (8), Dog (Canine) (7), Cat (Feline) (5), Goat (5), Mouse (Murine) (5), Pig (Porcine) (5), Rat (Rattus) (5), Chicken (2), Fish (2), Mammalian (2), Amphibian (1), Monkey (1)
|
|
Applications
|
Western Blotting (WB) (46), Enzyme Immunoassay (EIA) (42), Immunoprecipitation (IP) (31), Immunohistochemistry (Frozen Sections) (IHC (fro)) (30), ELISA (Capture) (5), ELISA (Detection) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), ELISA (2), Immunohistochemistry (IHC) (2), Radioimmunoassay (RIA) (2)
|
|
Epitopes
|
AA 1-23 (1), AA 117-126 (1), AA 143-152 (1), AA 148-158 (1), AA 27-39 (1), AA 65-74 (1), AA 69-86 (1)
|
