NPPA antibody

Catalog No. ABIN112557

The Mouse Monoclonal anti-NPPA antibody (Clone 23-01-14) (ABIN112557) specifically detects NPPA in IHC (p) and RIA. The antibody is reactive with Human samples.

Quick Overview for NPPA antibody (ABIN112557)

Target: NPPA (Natriuretic Peptide A (NPPA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)

Clone: 23-01-14

Product Details anti-NPPA Antibody

Specificity: This antibody reacts with ANP (whole molecule and residues 4-28).

Purification: Protein A chromatography

Immunogen: Synthetic peptide corresponding to part of the native molecule conjugated to Bovine Serum Albumin.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on paraffin sections. Radioimmunoassays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS buffer, pH 7.2, 10 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only.

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: Atrial Natriuretic Factor (ANF)

Background: Atrial natriuretic factor (ANP) is a potent vasoactive substance which is thought to play a key role in cardiovascular homeostasis and has a cGMP stimulating activity. There are two different prepronatriodilatin alleles. One codes for 2 Arginine residues at the C terminus that are cleaved to form the mature peptide, while the other ends in a termination codon immediately after the last codon of the mature peptide. ANP belongs to the natriuretic peptide family.Synonyms: ANP, Atrial Natriuretic Peptide, NPPA, PND, Prepronatriodilatin

Gene ID: 4878

NCBI Accession: NP_006163

UniProt: P01160