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Antibodies
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anti-Asialoganglioside GM1 antibody
Asialoganglioside GM1 antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN113230 |
| Quantity |
1 ml (2.3 mg/ml (OD280)) (Variants) |
| Price |
460.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Asialo GM1, GA1
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Immunogen
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Native, from brain
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Description
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Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized byhepatocytes. The AHSG molecule consists of two polypeptide chains, which are bothcleaved from a proprotein encoded from a single mRNA. It is involved in several functions,such as endocytosis, brain development and the formation of bone tissue. The protein iscommonly present in the cortical plate of the immature cerebral cortex and bone marrowhemopoietic matrix, and it has therefore been postulated that it participates in thedevelopment of the tissues. However, its exact significance is still obscure. It promotesendocytosis, possesses opsonic properties and influences the mineral phase of bone. Itshows affinity for calcium and barium ions.
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Specificity
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This antibody detects Asialo GM1. Species: Bovine. Others not tested.
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Application Notes
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ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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2.3 mg/ml (OD280)
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Buffer
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PBS, pH 7.2, containing 0.09 % Sodium Azide
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Storage
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Can be shipped at 2-8°C. Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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Research Area
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Metabolism
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Restrictions
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For Research Use only
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Publications
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Yoshino, Ariga, Latov et al.: "Fucosyl-GM1 in human sensory nervous tissue is a target antigen in patients with autoimmune neuropathies." in: Journal of neurochemistry, Vol. 61, Issue 2, pp. 658-63, 1993 (PubMed).
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Alternatives for antigen "Asialoganglioside GM1", type "Antibodies"
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Hosts
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Rabbit (4), Mouse (1)
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Reactivities
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Cow (Bovine) (2), Mouse (Murine) (1), Rat (Rattus) (1)
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Applications
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ELISA (3), Flow Cytometry (FACS) (1), Functional Studies (Func) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1), Western Blotting (WB) (1)
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Conjugates
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Biotin (1)
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