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Asialoganglioside GM1 antibody

Antigen

Asialoganglioside GM1

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Cow (Bovine)

Application
Alternatives Enzyme Immunoassay (EIA)
1 reference available
Catalog no. ABIN113230
Quantity 1 ml  (2.3 mg/ml (OD280))  (Variants)
Price 460.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: Asialo GM1, GA1
Immunogen Native, from brain
Description Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized byhepatocytes. The AHSG molecule consists of two polypeptide chains, which are bothcleaved from a proprotein encoded from a single mRNA. It is involved in several functions,such as endocytosis, brain development and the formation of bone tissue. The protein iscommonly present in the cortical plate of the immature cerebral cortex and bone marrowhemopoietic matrix, and it has therefore been postulated that it participates in thedevelopment of the tissues. However, its exact significance is still obscure. It promotesendocytosis, possesses opsonic properties and influences the mineral phase of bone. Itshows affinity for calcium and barium ions.
Specificity This antibody detects Asialo GM1. Species: Bovine. Others not tested.

Application Details

Application Notes ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 2.3 mg/ml (OD280)
Buffer PBS, pH 7.2, containing 0.09 % Sodium Azide
Storage Can be shipped at 2-8°C. Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Research Area Metabolism
Restrictions For Research Use only

Publications

Publications Yoshino, Ariga, Latov et al.: "Fucosyl-GM1 in human sensory nervous tissue is a target antigen in patients with autoimmune neuropathies." in: Journal of neurochemistry, Vol. 61, Issue 2, pp. 658-63, 1993 (PubMed).