BMP7 antibody (N-Term)

Catalog No. ABIN114065

The Rabbit Polyclonal anti-BMP7 antibody is suitable to detect BMP7 in samples from Human. It has been validated for EIA.

Quick Overview for BMP7 antibody (N-Term) (ABIN114065)

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP7 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-BMP7 Antibody

Binding Specificity: AA 1-17, N-Term

Sequence: S-T-G-S-K-Q-R-S-Q-N-R-S-K-T

Specificity: Detects Bone Morphogenetic Protein 7 /BMP7.

Purification: Ammonium Sulphate Fractionation

Immunogen: Synthetic peptide corresponding to the amino acids 1-14 of the native molecule conjugated to Keyhole limpet Haemocyanin.

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 3.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Alternative Name: BMP7

Background: Bone Morphogenetic Protein 7 (BMP7), also known as osteogenic protein 1 (OP1), is produced from a DNA sequence encoding the human BMP2 signal peptide and human BMP2 propeptide (amino acid residues 1 to 282) fused to the human BMP7 mature subunit (amino acid residues 293 to 431). Mature human BMP7, generated after the proteolytic removal of the signal peptide and the propeptide, is a disulfide linked homodimeric protein, comprised of two 139 amino acid residue subunits. Bone Morphogenetic Proteins (BMP) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species.Synonyms: BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1

Gene ID: 655, 9606

UniProt: P18075

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance