Chorionic Gonadotropin (hCG) antibody

Details for Product No. ABIN115292
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Antigen
Synonyms CGB, CGB7, CGB1
Reactivity
Human
(135), (2), (2), (1)
Host
Rabbit
(114), (17), (6), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(102), (33), (30), (28), (14), (8), (7), (6), (6), (5), (3), (2), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 1 mL
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Catalog No. ABIN115292
253.00 $
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Immunogen Beta chain of human chorionic gonadotropin.
Specificity This antibody reacts with hCG. Cellular Localization: Cytoplasmic
Purification Purified
Background It stains strongly with the human placenta and placental trophoblasts.
Alternate names: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta
Gene ID 1082
NCBI Accession NP_000728
UniProt P01233
Research Area Hormones
Application Notes Immunohistochemistry on paraffin embedded sections: diluted of 1: 100-1: 500 in an ABC method (30 minutes at room temperature)Recommended Positive Control: PlacentaAlthough not required, proteolytic treatment of formalin fixed paraffin embedded tissuesections may enhance the immunostaining in overfixed tissues. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer containing sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
General Kipreos, Lander, Wing et al.: "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family." in: Cell, Vol. 85, Issue 6, pp. 829-39, 1996 (PubMed).

Pagano: "Cell cycle regulation by the ubiquitin pathway." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 11, Issue 13, pp. 1067-75, 1997 (PubMed).

Michel, Xiong: "Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 9, Issue 6, pp. 435-49, 1998 (PubMed).

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