CD8 antibody

Catalog No. ABIN1177373

Product Details anti-CD8 Antibody

Target: CD8

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Brand: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone: HIT8a

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Target Details for CD8

Target: CD8

Alternative Name: CD8 (CD8 Products)

Background: Reacts with the alpha subunit (32 kDa) of the two-chain complex. CD8 molecule binds to HLA class I molecules during interaction of CD8+ T cells with antigen-presenting cells or with target cells. CD8 is expressed on T cytotoxic/suppressor cell populations. HIT8a stains approximately 13 - 48% of peripheral blood lymphocytes and 80% of thymocytes, as well as a subset of NK cells. Clones HIT8a and RPA-T8 (Cat. No. 555364) are not cross-blocking.