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Details for Product No. ABIN118693

Integrin alpha 1 (ITGA1) antibody

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Antigen
Synonyms VLA1, CD49a, Vla1, CD49A, E130012M19Rik
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN118693
Quantity 0.2 mg
Price
577.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Clone TS2-7
Isotype IgG1
Specificity This antibody recognises the alpha 1 integrin sub-unit, which forms the VLA-1 heterodimer in association with the beta 1 integrin.
Purification Affinity Chromatography on Protein G
Alternative Name CD49a / ITGA1
Background VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells.
Alternate names: CD49 antigen-like family member A, ITGA-1, Integrin alpha-1, Laminin and Collagen Receptor, VLA-1, VLA1
Gene ID 3672
NCBI Accession NP_852478.1
UniProt P56199
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 ul of 1/25-1/50 diluted antibody to label 10e6 cells in 100 ul. Immunoprecipitation. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hemler, Sanchez-Madrid, Flotte et al.: "Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 132, Issue 6, pp. 3011-8, 1984 (PubMed).

Hemler, Jacobson, Strominger: "Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells." in: The Journal of biological chemistry, Vol. 260, Issue 28, pp. 15246-52, 1986 (PubMed).

Hafler, Hemler, Christenson et al.: "Investigation of in vivo activated T cells in multiple sclerosis and inflammatory central nervous system diseases." in: Clinical immunology and immunopathology, Vol. 37, Issue 2, pp. 163-71, 1985 (PubMed).

Alternatives for antigen "Integrin alpha 1 (ITGA1)", type "Antibodies"
Hosts (35), (31), (2)
Reactivities (65), (24), (24), (12), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (29), (27), (15), (15), (13), (10), (8), (7), (3), (2), (2), (2), (1), (1), (1)
Conjugates (7), (7), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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