CD31 antibody (Biotin)

Catalog No. ABIN120450

The Biotin-conjugated Mouse Monoclonal anti-CD31 antibody (Clone TLD-3A12) (ABIN120450) specifically detects CD31 in FACS. The antibody is reactive with Rat samples.

Quick Overview for CD31 antibody (Biotin) (ABIN120450)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD31 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: TLD-3A12

Product Details anti-CD31 Antibody (Biotin)

Specificity: This antibody recognises PECAM-1 (CD31). Clone TLD-3A12 has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen.

Purification: Affinity chromatography on Protein G

Immunogen: Activated, Lewis rat derived microglial cells. Spleen cells from immunised BALB/c mouse were fused with cells of the mouse SP2 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31 / PECAM1

Background: CD31 is a type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leucocytes.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule

Gene ID: 29583

NCBI Accession: NP_113779

UniProt: Q3SWT0

Pathways: Regulation of Actin Filament Polymerization