Transferrin Receptor antibody (FITC)

Catalog No. ABIN120506

The Mouse Monoclonal anti-Transferrin Receptor antibody has been validated for FACS. It is suitable to detect Transferrin Receptor in samples from Rat.

Quick Overview for Transferrin Receptor antibody (FITC) (ABIN120506)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: OX-26

Product Details anti-Transferrin Receptor Antibody (FITC)

Purification: Affinity chromatography on Protein G

Immunogen: PHA activated rat lymphocytes. Spleen cells from immunised Balb/c mice were fused with cells from the NS1 mouse myeloma cell line.

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 / TFRC

Background: CD71 is a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimers, Parkinsons, Huntingtons and Multiple Sclerosis.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gene ID: 10116

UniProt: Q99376

Pathways: Transition Metal Ion Homeostasis