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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Adiponectin, C1Q and Collagen Domain Containing (ADIPOQ) antibody
|Synonyms||ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, adiponectin, APN, Acdc, apM1, 30kDa, adipo, Acrp30, ADIPOQ, MGC138982, ADN, MGC84292|
Human, Mouse (Murine)
Alternatives ELISA, Western Blotting (WB)
|4 references available|
|Quantity||0.1 mL (1.0 mg/ml) (Variants)|
|Price||396.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 6 to 8 Business Days|
|Immunogen||Recombinant human adiponectin (15-244 aa) purified from E. coli|
|Cross-Reactivity||Human, Mouse (Murine)|
|Description||Human Adiponectin, also referred to as AdipoQ, Acrp30, apm-1 or GBP28, is a secreted protein expressed exclusively in differentiated adipocyte (adipokine). Adiponectin contains a modular structure comprising an N-terminal collagenous domain followed by a C-terminal globular domain (gAcrp30). Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia. Alternate Names: ACRP30, ADIPOQ, ACDC, APM1, APM-1, GBP28, Adipocyte, C1q and collagen domain-containing protein, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein.|
|Application Notes||ELISA. Western blot (1:250 - 1:1,000), recommended starting dilution is 1:500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.|
|Buffer||PBS, pH 7.4, containing 0.02% thimerosal|
|Storage||Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.|
|Research Area||Cancer, Atherosclerosis, Metabolism, Hormones|
|Restrictions||For Research Use only|
Maeda, Okubo, Shimomura et al.: "cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)." in: Biochemical and biophysical research communications, Vol. 221, Issue 2, pp. 286-9, 1996 (PubMed).
Berg, Combs, Du et al.: "The adipocyte-secreted protein Acrp30 enhances hepatic insulin action." in: Nature medicine, Vol. 7, Issue 8, pp. 947-53, 2001 (PubMed).
Berg, Combs, Scherer: "ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism." in: Trends in endocrinology and metabolism: TEM, Vol. 13, Issue 2, pp. 84-9, 2002 (PubMed).
Yamauchi, Kamon, Minokoshi et al.: "Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase." in: Nature medicine, Vol. 8, Issue 11, pp. 1288-95, 2002 (PubMed).