CA2 antibody

Catalog No. ABIN121484

The Sheep Polyclonal anti-CA2 antibody is suitable to detect CA2 in samples from Human. It has been validated for WB and ID.

Quick Overview for CA2 antibody (ABIN121484)

Target: CA2 (Carbonic Anhydrase II (CA2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This CA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunodiffusion (ID)

Product Details anti-CA2 Antibody

Purification: Ion exchange chromatography

Immunogen: Purified human carbonic anhydrase II (CAII) prepared from erythrocytes

Application Details

Application Notes: Western Blot: 1/1000. Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Glycine buffered saline pH 7.4 containing 0.09 % Sodium Azide, 0.1 % EACA, 1 mM EDTA and 0.01 % Benzamidine

Preservative: Sodium azide, Benzamidine, EACA

Precaution of Use: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: Carbonic Anhydrase 2

Background: Carbonic anhydrase II (CAII) is a single polypeptide chain of molecular weight 29 kDa. It is present in the cytosol of most tissues, but highest concentrations are found, like Carbonic Anhydrase I, in erythrocytes. The concentration in erythrocytes is about 20μM. It catalyses the hydration of CO2 and the hydrolysis of esters. Zn2+ ion cofactor is required for enzyme activity. Certain point mutations occur without apparent clinical effect, however, complete absence leads to mild mental retardation and cerebral calcification, osteoporosis and renal tubular acidosis.Synonyms: CA-II, CA2, CAC, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II

UniProt: P00918