LPAR5 antibody

Catalog No. ABIN122193

The Rabbit Polyclonal anti-LPAR5 antibody (ABIN122193) specifically detects LPAR5 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for LPAR5 antibody (ABIN122193)

Target: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LPAR5 Antibody

Specificity: Reacts to G Protein-Coupled Receptor GPR92/GPR93 (Family: GPCR, Subfamily: Orphan-A)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 1.5 -4 μg/mL (for details please see Protocols below).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for LPAR5

Target: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Alternative Name: LPAR5 / GPR92 / GPR93

Background: GPR92/GPR93 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity and led to an increase in both phosphoinositide hydrolysis and c-AMP production. GPR92 is atypical in that it has a low sequence homology with the classic LPA receptors (21-22 % ). The expression of GPR92 is mainly found in brain, testis, heart, placenta, spleen, lung, and gut. Notably, GPR92 is highly expressed in the lymphocyte compartment of the gastrointestinal tract. It is the most abundant GPCR that is activated by LPA found in the small intestinal intraepithelial CD8+ cytotoxic T cells.Synonyms: 93, G-protein coupled receptor 92, LPA receptor 5, LPA-5, Lysophosphatidic acid receptor 5

Gene ID: 57121

UniProt: Q9H1C0