Immunohistochemistry on paraffin embedded sections: 17 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
PBS, pH 7.7, containing 0.01 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-80 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
CNR2
(Cannabinoid Receptor 2 (CNR2))
Alternative Name
Cannabinoid Receptor 2
Background
CB2 Cannabinoid receptors are present in the immune system and are associated with producing antinociception to external stimuli, such as temperature. Unlike CB(1) receptors, CB(2) receptors are expressed in the periphery, and not the central nervous system. CB2 expression has been reported in tissues of the immune system, including spleen and tonsil. In blood, CB2 is highest in B-cells > natural killer cells >> monocytes > polymorphonuclear neutrophil cells > T8 cells > T4 cells. ESTs have been isolated from blood, lymph, placenta, and tonsil libraries.Synonyms: CB-2, CB2, CNR2, CX5, hCB2