Lipoprotein Lipase antibody
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- Target See all Lipoprotein Lipase (LPL) Antibodies
- Lipoprotein Lipase (LPL)
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Reactivity
- Human, Cow
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Lipoprotein Lipase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Specificity
- This Monoclonal antibody is directed against the CII binding site. Blocks the catalytic activity of Bovine milk lipase. A small partial cross-reactivity with Human Heparin Plasma Lipase activity was observed (Ref. 1).
- Cross-Reactivity (Details)
- Species reactivity (tested):Bovine, weak cross-reactivity with Human.
- Purification
- Affinity Chromatography on Protein A
- Immunogen
- Purified Bovine Lipoprotein Lipase
- Clone
- Mab-7
- Isotype
- IgG1
- Top Product
- Discover our top product LPL Primary Antibody
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- Application Notes
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ELISA. Immunoblotting. Immunohistochemistry (1/10). Dilution buffer: PBS with 0.5 % BSA and 0.1 % Na-Azide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1 mL distilled water
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Lipoprotein Lipase (LPL)
- Alternative Name
- Lipoprotein Lipase (LPL Products)
- Synonyms
- HDLCQ11 antibody, LIPD antibody, fb62e04 antibody, fc49b03 antibody, wu:fb62e04 antibody, wu:fc49b03 antibody, LPL antibody, lipd antibody, hdlcq11 antibody, lpl antibody, LOC100223817 antibody, lipoprotein lipase antibody, LPL antibody, Lpl antibody, lpl antibody
- Background
- Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.Synonyms: EC=3.1.1.34, LIPD, LPL
- Gene ID
- 4023
- NCBI Accession
- NP_000228
- UniProt
- P06858
- Pathways
- Lipid Metabolism
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