DAP
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 20 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Background
Death Associated Protein 1 (DAP1) is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-gamma. The DAP1 protein is praline-rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites. The protein is localized in the cytoplasma, however the detailed mechanism of its proapoptotic function is unclear.Synonyms: DAP, DAP-1, DAP1