DIDO1 antibody (N-Term)

Catalog No. ABIN127222

This Rabbit Polyclonal antibody specifically detects DIDO1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for DIDO1 antibody (N-Term) (ABIN127222)

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIDO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DIDO1 Antibody

Binding Specificity: N-Term

Specificity: The antibody recognizes the 62 kDa Dio-1.

Purification: Protein A affinity purified

Immunogen: Synthetic peptide near the N-terminus of mouse Dio-1.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate and mouse small intestine tissue lysate can beused as positive controls.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for DIDO1

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Alternative Name: DIDO1

Background: Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus, and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression.Synonyms: C20orf158, DATF1, Death-inducer obliterator 1, KIAA0333

Gene ID: 11083

NCBI Accession: NP_001180298

UniProt: Q9BTC0

Pathways: Hormone Activity