L-Selectin antibody

Catalog No. ABIN127260

The Rabbit Polyclonal anti-L-Selectin antibody (ABIN127260) specifically detects L-Selectin in WB, IP and IHC (p). The antibody is reactive with Human samples.

Quick Overview for L-Selectin antibody (ABIN127260)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L-Selectin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-L-Selectin Antibody

Specificity: The antibody recognizes L-Selectin.

Purification: Protein A chromatography

Immunogen: Synthetic peptide surrounding amino acid 69 of human L-Selectin.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA as stabilizer and 0.01 % thimerosal as preservative

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: CD62L / L-Selectin

Target Type: Chemical

Background: Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (also called ELMA-1) expressed on endothelial cells. L-Selectin (also called LECAM-1) is expressed on the majority of B and naive T cells and on most monocytes, neurophils and eosinophils. P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils.Synonyms: CD62 antigen-like family member L, LAM-1, LECAM1, LNHR, LYAM1, Leu-8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, SELL, TQ1, gp90-MEL

Gene ID: 6402

NCBI Accession: NP_000646

UniProt: P14151