BCLAF1 antibody

Catalog No. ABIN127331

The Rabbit Polyclonal anti-BCLAF1 antibody is suitable to detect BCLAF1 in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for BCLAF1 antibody (ABIN127331)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-BCLAF1 Antibody

Specificity: The antibody recognizes the BTF.

Purification: Affinity Purified

Immunogen: Synthetic peptide of human BTF

Application Details

Application Notes: Western Blot: 1: 500-1: 2000. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 30 % glycerol, 1 % BSA and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1 / BTF

Background: BTF is a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. BTF localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this protein.Synonyms: Aa2-041, Bcl-2-associated transcription factor 1, KIAA0164

Gene ID: 9774

NCBI Accession: NP_001070908

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus