CD31 antibody

Catalog No. ABIN135196

This Rat Monoclonal antibody specifically detects CD31 in FACS, IP, ICC, IHC (fro) and BR. It exhibits reactivity toward Mouse.

Quick Overview for CD31 antibody (ABIN135196)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: 390

Product Details anti-CD31 Antibody

Purpose: Rat Anti-Mouse CD31-LE/AF

Specificity: Mouse CD31, Mr 130-140 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD31 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.

Endotoxin Level: Low Endotoxin

Immunogen: C3H/HeJ mouse hematopoietic progenitor cell line 32D

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background: CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and paltelets. CD31 interacts homotypically in cell adhesion assays. MAb 390 inhibits the aggregation of L cells transfected with a variant form of CD31.

Gene ID: 18613

UniProt: Q08481

Pathways: Regulation of Actin Filament Polymerization