TCRgd antibody

Details for Product No. ABIN135302
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Mouse (Murine)
(31), (6), (6), (4)
(31), (16)
Clonality (Clone)
Monoclonal ()
(10), (10), (4), (2), (2), (2), (1)
Flow Cytometry (FACS), Immunoprecipitation (IP)
(47), (9), (8), (3)
Pubmed 2 references available
Catalog no. ABIN135302
Quantity 0.5 mg
244.20 $   Plus shipping costs $45.00
Shipping to United States (Change)
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Clone UC7-13D5
Isotype IgG
Characteristics The antibody detects: T-cell receptor (TCR) complex
The monoclonal antibody UC7-13D5 is specific for the heterodimer and plate-bound UC7-13D5 activates TCR-bearing cells. This antibody does not react with TCR-expressing T cells.
Purification Purified
Purity Purified
Background The TCR heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are + and have limited receptor diversity. The TCR heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.
Application Notes Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

In vivo depletion of gd TCR-expressing T cell

Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
General Barrett, Hedrick, Dent et al.: "Control of self-reactivity in the intestine." in: Immunologic research, Vol. 10, Issue 3-4, pp. 341-8, 1992 (PubMed).

Davis: "T cell receptor gene diversity and selection." in: Annual review of biochemistry, Vol. 59, pp. 475-96, 1990 (PubMed).

Hosts (31), (16)
Reactivities (31), (6), (6), (4)
Applications (47), (9), (8), (3)
Conjugates (10), (10), (4), (2), (2), (2), (1)
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