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CD9 antibody (CD9)

Details for Product anti-CD9 Antibody No. ABIN135677, Supplier: Login to see
Antigen
  • Tspan29
  • BTCC-1
  • DRAP-27
  • MIC3
  • MRP-1
  • TSPAN-29
  • TSPAN29
Reactivity
Human
344
83
28
25
21
21
21
20
13
8
7
7
7
7
6
6
1
1
Host
Mouse
278
77
55
Clonality (Clone)
Monoclonal ()
Conjugate
This CD9 antibody is un-conjugated
58
56
33
16
5
5
3
2
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
306
188
95
74
63
45
45
38
27
26
5
4
3
2
2
2
2
2
1
1
Supplier
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Clone MM2-57
Isotype IgG2b
Characteristics The antibody detects: Human CD9
Purification Purified
Alternative Name CD9 (CD9 Antibody Abstract)
Background CD9 is a 24 kDa member of the transmembrane 4 superfamily (TM4-SF) of cell surface receptors. It is expressed strongly on platelets, lymphoid progenitor cells, activated lymphocytes and endothelia, and, weakly, on eosinophils, granulocytes, monocytes, and macrophages. CD9 functions as an adhesion molecule where it mediates platelet aggregation and activation.
Research Area Embryogenesis, Embryonic stem cells, Reproduction, CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Working Dilution:
FACS: 1 µg/10^5 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Comment

platelet inhibition and aggregation studies

Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Product cited in: Kamisasanuki, Tokushige, Terasaki et al.: "Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: a novel antiangiogenic therapy." in: Biochemical and biophysical research communications, Vol. 413, Issue 1, pp. 128-35, 2011 (PubMed).

Background publications Wright, Tomlinson: "The ins and outs of the transmembrane 4 superfamily." in: Immunology today, Vol. 15, Issue 12, pp. 588-94, 1995 (PubMed).