ADCY10 antibody (N-Term)

Catalog No. ABIN1449834

Product Details anti-ADCY10 Antibody

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Rabbit, Bovine, DogSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the N terminal of human SAC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for ADCY10

Target: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Alternative Name: ADCY10 / SAC (ADCY10 Products)

Background: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene.Synonyms: Adenylate cyclase homolog, Adenylate cyclase type 10, Germ cell soluble adenylyl cyclase, Testicular soluble adenylyl cyclase

Gene ID: 55811

NCBI Accession: NP_060887

Pathways: cAMP Metabolic Process