AP3M2 antibody (Middle Region)

Catalog No. ABIN1449881

The Rabbit Polyclonal anti-AP3M2 antibody has been validated for WB. It is suitable to detect AP3M2 in samples from Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for AP3M2 antibody (Middle Region) (ABIN1449881)

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AP3M2 Antibody

Binding Specificity: Middle Region

Sequence: VVNTITGSTN VGDQLPTGQL SVVPWRRTGV KYTNNEAYFD VIEEIDAIID

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine, Dog, Pig, Rabbit, Chicken Xenopus, ZebrafishSpecies reactivity (tested):Human.

Purification: Purified using immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AP3M2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for AP3M2

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Alternative Name: AP3 Complex Subunit mu-2 / AP3M2

Background: AP3M2 is part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles.Synonyms: Adapter-related protein complex 3 mu-2 subunit, Clathrin assembly protein assembly protein complex 1 medium chain homolog 2, Clathrin coat assembly protein AP47 homolog 2, Clathrin coat-associated protein AP47 homolog 2, Golgi adaptor AP-1 47 kDa protein homolog 2, HA1 47 kDa subunit homolog 2, Mu3B-adaptin, P47B

Gene ID: 10947

NCBI Accession: NP_006794