T-Complex-Associated-Testis-Expressed 3 (TCTE3) (N-Term) antibody

Details for Product No. ABIN1450006
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms D17Leh117c, LC2, Tcte-3, Tctex-2, Tctex-4, Tctex2, Tctex4, TCTEX1D3
Epitope
N-Term
(3), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(4), (2), (2)
Host
Rabbit
(3), (1)
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(4), (3), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen 19 amino acid synthetic peptide near the amino terminus of Human TCTEX1D3
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Affinity chromatography purified via peptide column
Alternative Name TCTE3
Background Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH).Synonyms: T-complex testis-specific protein 3, T-complex-associated testis-expressed protein 3, TCTEX1D3, Tcte-3, Tctex1 domain-containing protein 3
Molecular Weight 22 kDa
Gene ID 6991
NCBI Accession NP_777570
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Teshiba, Masumoto, Esumi et al.: "Identification of TCTE3 as a gene responsible for congenital diaphragmatic hernia using a high-resolution single-nucleotide polymorphism array." in: Pediatric surgery international, Vol. 27, Issue 2, pp. 193-8, 2011 (PubMed).

Chuang, Yeh, Bollati et al.: "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth." in: Developmental cell, Vol. 9, Issue 1, pp. 75-86, 2005 (PubMed).

Li, Lee, Cooper: "NudEL targets dynein to microtubule ends through LIS1." in: Nature cell biology, Vol. 7, Issue 7, pp. 686-90, 2005 (PubMed).

He, Francis, Myers et al.: "Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 697-703, 2005 (PubMed).

Watanabe, Fujiwara, Shimizu et al.: "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q." in: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 153-6, 1996 (PubMed).

Validation Images
Catalog No. ABIN1450006
401.50 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
401.50 $

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?