ASB14 antibody (N-Term)

Catalog No. ABIN1544918

The Rabbit Polyclonal anti-ASB14 antibody is suitable to detect ASB14 in samples from Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit and Rat. It has been validated for WB.

Quick Overview for ASB14 antibody (N-Term) (ABIN1544918)

Target: ASB14 (Ankyrin Repeat and SOCS Box Containing 14 (ASB14))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB14 Antibody

Binding Specificity: N-Term

Sequence: LELLIQAGFD VNFMLDQRIN KHYDDHRKSA LYFAVSNSDL SSVKLLLSAG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ASB14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ASB14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 302 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB14

Target: ASB14 (Ankyrin Repeat and SOCS Box Containing 14 (ASB14))

Alternative Name: ASB14

Background: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: DKFZp313L0121
Protein Interaction Partner: PGAM5, PHB2, RPL23, VAPA, CUL5, VDAC1, TUFM, TCEB2, TCEB1, SSR4, SLC25A1, RPS16, NOTCH2, GALK1, EMD, CYC1, ATP2A2, ARF4, SLC25A6, SLC25A5,
Protein Size: 302

Molecular Weight: 33 kDa

Gene ID: 142686

NCBI Accession: NM_130387, NP_569058

UniProt: A6NK59