CD31 antibody

Catalog No. ABIN155166

The Mouse Monoclonal anti-CD31 antibody (Clone 158-2B3) (ABIN155166) specifically detects CD31 in FACS, IF and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CD31 antibody (ABIN155166)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 158-2B3

Product Details anti-CD31 Antibody

Purification: Protein G Chromatography.

Immunogen: Stimulated human leukocytes

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry. Immunoflourescence. Immunohistochemistry on Aceton-Fixed Frozen Sections. Does not work in Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: 10 mM PBS pH 7.4, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31 / PECAM1

Background: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule

Gene ID: 9606

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization