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HTRA2 antibody
HTRA2
Reactivity: Human, Mouse
WB, ELISA
Host: Mouse
Monoclonal
1B3
unconjugated
Product Details anti-HTRA2 Antibody
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Target
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HTRA2
(HtrA Serine Peptidase 2 (HTRA2))
Reactivity
All reactivities for HTRA2 antibodies
Human, Mouse
Host
All hosts for HTRA2 antibodies
Mouse
Clonality
All clonalities for HTRA2 antibodies
Monoclonal
Conjugate
All conjugates for HTRA2 antibodies
This HTRA2 antibody is un-conjugated
Application
All applications for HTRA2 antibodies
Western Blotting (WB), ELISA
Purification
The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Immunogen
Recombinant HtrA2/Omi, Accession / GI number: NP_037379
Clone
1B3
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Recommended dilution 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1mg/ml
Buffer
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for HTRA2
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Target
HTRA2
(HtrA Serine Peptidase 2 (HTRA2))
Alternative Name
HtrA2/Omi (HTRA2 Products )
Synonyms
CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
Background
HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death
Pathways
Positive Regulation of Endopeptidase Activity
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