GNA11 antibody

Catalog No. ABIN3023415

The Rabbit Polyclonal anti-GNA11 antibody has been validated for WB and IHC. It is suitable to detect GNA11 in samples from Human.

Quick Overview for GNA11 antibody (ABIN3023415)

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNA11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GNA11 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human GNA11

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNA11

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Alternative Name: GNA11

Background: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.,GNA11,FBH,FBH2,FHH2,GNA-11,HHC2,HYPOC2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,mTOR Signaling Pathway,GNA11

Molecular Weight: 42 kDa

Gene ID: 2767

UniProt: P29992

Pathways: G-protein mediated Events