Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) (AA 1-49) antibody

Catalog No. ABIN1724826

Product Details

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Binding Specificity: AA 1-49

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: P2RY13 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human P2RY13 (AA: 1-49) expressed in E. Coli.

Clone: 2H1G9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References

Syu, Wang, Ma, Liu, Pearce, Prakash, Henson, Weng, Ghosh, Ramos, Eichinger, Pino, Dong, Xiao, Wang, Tao, Kim, Desai, Zhu: "Development and application of a high-content virion display human GPCR array." in: Nature communications, Vol. 10, Issue 1, pp. 1997, (2019) (PubMed).

Luttrell: "Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors." in: Molecular biotechnology, Vol. 39, Issue 3, pp. 239-64, (2008) (PubMed).

Zhang, Luo, Gustafson, Palmer, Qiao, Fan, Yang, Laz, Bayne, Monsma: "P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse." in: The Journal of pharmacology and experimental therapeutics, Vol. 301, Issue 2, pp. 705-13, (2002) (PubMed).

Target Details

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Alternative Name: P2RY13 (P2RY13 Products)

Background:

Description: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP.

Aliases: GPCR1, GPR86, GPR94, P2Y13, SP174, FKSG77

Molecular Weight: 40.8kDa

Gene ID: 53829

HGNC: 53829

UniProt: Q9BPV8

Pathways: cAMP Metabolic Process