The Mouse Monoclonal anti-Canine Heartworm antibody (Clone HW1-39) (ABIN180864) specifically detects Canine Heartworm in WB and EIA.
The antibody is reactive with Dog samples.
ELISA. Western Blot: detects band/s of approximately 170, 155, 98, 80, 70 and 62 kDa underreducing conditions. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0mg/mL
Buffer
PBS, pH 7.2 containing 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
Canine Heartworm
(Heartworm, Canine)
Alternative Name
Canine Heartworm
Background
Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans. Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.Synonyms: Dirofilaria immitis