EMR2 antibody (PE)

Catalog No. ABIN1819810

Product Details anti-EMR2 Antibody (PE)

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EMR2 antibody is conjugated to PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Recognizes human EMR2, a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of proteins, which is closely related to CD97. EMR2, also known as CD312, is predominantly expressed on myeloid dendritic cells, monocytes and tissue macrophages. Various isoforms of EMR2 have been documented. The ligand for the largest isoform of EMR2 has recently been identified as chrondroitin sulphate, which binds to the fourth EGF-like module of EMR2. Clone 2A1 specifically recognizes the stalk region of EMR2.

Purification: Protein G purified

Immunogen: NIH-3T3 cells stably transfected with EMR2 (EGF1-5) cDNA.

Type of Immunogen: Cells

Clone: 2A1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-Fr, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Protect from light.

Storage: 4 °C,-20 °C

Storage Comment: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Target Details for EMR2

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Alternative Name: ADGRE2 / EMR2 (EMR2 Products)

Background: Name/Gene ID: ADGRE2
Subfamily: Orphan-B
Family: GPCR

Synonyms: ADGRE2, CD312 antigen, EMR2, EGF-like module receptor 2, CD312

Gene ID: 30817