EMR2 antibody (AA 451-550)
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- Target See all EMR2 Antibodies
- EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))
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Binding Specificity
- AA 451-550
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EMR2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EMR2/CD312
- Isotype
- IgG
- Top Product
- Discover our top product EMR2 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))
- Alternative Name
- EMR2/CD312 (EMR2 Products)
- Synonyms
- EMR2 antibody, CD312 antibody, adhesion G protein-coupled receptor E2 antibody, ADGRE2 antibody, LOC484898 antibody
- Background
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Synonyms: CD 312, CD 312 antigen, CD312, CD312 antigen, Egf like module containing mucin like hormone receptor like 2, Egf like module containing mucin like hormone receptor like sequence 2, EGF like module EMR2, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2, EMR2, EMR2_HUMAN, ADGRE2, adhesion G protein-coupled receptor E2.
Background: The epidermal growth factor (EGF) family constitutes a group of class B, G protein-coupled receptors, which includes CD97 and EMR2. EMR2 is a member of the EGF-TM7 receptor subfamily. EGF-TM7 receptors are a family of class B, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system. Within the TM7 superfamily, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique. Derived from the processing of a single polypeptide, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety. Through a variable number of N-terminal EGF-like domains, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate. EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes. EMR2 is proteo-lytically cleaved into two separate subunits: a seven-transmembrane subunit, and an extracellular Alpha subunit.
- Gene ID
- 30817
- UniProt
- Q9UHX3
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