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MAX Dimerization Protein 3 (MXD3) antibody

Antigen

MAX Dimerization Protein 3 (MXD3)

Synonyms MYX, MAD3, BHLHC13, MGC2383, FLJ35523, Mad3, bHLHc13, 4631412E13Rik, Myx, Mad, MGC66281, zgc:66281, MXD3
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Cow (Bovine), Human, Mouse (Murine), Dog (Canine)

Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN182330
Quantity 0.1 mg  (Variants)
Price 251.90 $   Plus shipping costs $45.00
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Additional Information

Alternative name MAD3
Gene ID MXD3
UniProt Q9BW11
Immunogen The immunogen for anti-MXD3 antibody: synthetic peptide directed towards the N terminal of human MXD3
Sequence PIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLER LKQQMPLGAD
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine)
Format Lyophilized
Reconstitution Add 100 µl of distilled water. Final anti-MXD3 antibody concentration is 1 mg/ml.
Description MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Characteristics Antigen Size: 206 amino acids
Molecular Weight 23kDa

Application Details

Application Notes WB Suggested Anti-MXD3 Antibody Titration: 0.5ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T.
Purification Protein A purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only

Publications

Product Suzuki, Yoshitomo-Nakagawa, Maruyama et al.: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, 1997 (PubMed).

Alternatives

Alternatives for antigen "MAX Dimerization Protein 3 (MXD3)", type "Antibodies"
Hosts Rabbit (6), Goat (4)
Reactivities Human (8), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Mouse (Murine) (1), Rat (Rattus) (1), Xenopus laevis (1), Zebrafish (1)
Applications Western Blotting (WB) (6), ELISA (5), Immunohistochemistry (IHC) (2), Dot Blot (DB) (1), Immunocytochemistry (ICC) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
Epitopes Internal Region (2), N-Term (2), C-Term (1)