HOXA13 antibody (Middle Region)

Catalog No. ABIN182456

The Rabbit Polyclonal anti-HOXA13 antibody has been validated for WB. It is suitable to detect HOXA13 in samples from Human, Mouse and Dog. There is 1 publication available.

Quick Overview for HOXA13 antibody (Middle Region) (ABIN182456)

Target: HOXA13 (Homeobox A13 (HOXA13))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXA13 Antibody

Binding Specificity: Middle Region

Sequence: AAAAANQCRN LMAHPAPLAP GAASAYSSAP GEAPPSAAAA AAAAAAAAAA

Predicted Reactivity: Dog: 83%, Human: 100%, Mouse: 92%

Characteristics: This is a rabbit polyclonal antibody against HOXA13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXA13 antibody (ABIN182456)

Villavicencio-Lorini, Kuss, Friedrich, Haupt, Farooq, Türkmen, Duboule, Hecht, Mundlos: "Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation." in: The Journal of clinical investigation, Vol. 120, Issue 6, pp. 1994-2004, (2010) (PubMed).

Target Details for HOXA13

Target: HOXA13 (Homeobox A13 (HOXA13))

Alternative Name: HOXA13

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Alias Symbols: HOX1, HOX1J
Protein Interaction Partner: UBC, MEIS3, SMAD5, MEIS2, MEIS1, SMAD1, SMAD2,
Protein Size: 388

Molecular Weight: 40 kDa

Gene ID: 3209

NCBI Accession: NM_000522, NP_000513

UniProt: P31271